Exploring neutron capture therapy with 33S and 10B

The S-33(n,alpha)Si-30 reaction was proposed as cooperative neutron capturer to B-10(n,alpha)Li-7 in Neutron Capture Therapy (NCT). At that moment, the available S-33(n,alpha)Si-30 cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. These new data are used for the calculation of the dose rate on ICRU-4 tissue by using kerma factors, a simplified model of tissue and a 13.45 keV neutron beam, energy of the most important S-33 (n,alpha)Si-30 resonance. A significant enhancement of the dose rate due to the presence of S-33 is shown. In spite of the limitations, the cooperative action of S-33 and B-10 is an interesting possibility to be studied for accelerator-based neutron sources with non-moderated neutrons.