Long-Term Efficacy and Safety of Copanlisib in Multiply Relapsed or Refractory Patients with Marginal Zone Lymphoma

被引:1
|
作者
Dreyling, Martin [1 ]
Panayiotidis, Panayiotis [2 ]
Follows, George A. [3 ]
Mollica, Luigina [4 ]
Nagler, Arnon [5 ]
Ozcan, Muhit [6 ]
Santoro, Armando [7 ]
Stevens, Don [8 ]
Trevarthen, David [9 ]
Hiemeyer, Florian [10 ]
Liu, Li [11 ]
Garcia-Vargas, Jose [11 ]
Childs, Barrett H. [11 ]
Zinzani, Pier Luigi [12 ]
机构
[1] Univ Hosp LMU, Dept Med 3, Munich, Germany
[2] Natl & Kapodistrian Univ Athens, Sch Med, Athens, Greece
[3] Cambridge Univ Hosp NHS Fdn Trust, Cambridge, England
[4] Maisonneuve Rosemont Hosp Res Ctr, Montreal, PQ, Canada
[5] Tel Aviv Univ, Chaim Sheba Med Ctr, Tel Hashomer, Israel
[6] Ankara Univ, Ankara, Turkey
[7] Humanitas Clin & Res Ctr, Rozzano, Italy
[8] Norton Canc Inst, Louisville, KY USA
[9] Comprehens Canc Care & Res Inst Colorado, Englewood, CO USA
[10] Bayer AG, Div Pharmaceut, Berlin, Germany
[11] Bayer HealthCare Pharmaceut Inc, Whippany, NJ USA
[12] Univ Bologna, Inst Hematol Seragnoli, Bologna, Italy
关键词
D O I
10.1182/blood-2019-121932
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1531
引用
收藏
页数:5
相关论文
共 50 条
  • [41] DURABLE RESPONSES WITH IDELALISIB MONOTHERAPY IN PATIENTS (PTS) WITH RELAPSED OR REFRACTORY MARGINAL ZONE LYMPHOMA (MZL)
    Gyan, E.
    Martin, P.
    Armas, A.
    Gopal, A. K.
    Wagner-Johnston, N. D.
    Abella-Dominicis, E.
    Ye, W.
    Philip, B.
    Sorenson, B.
    Walewski, J.
    de Vos, S.
    HAEMATOLOGICA, 2016, 101 : 757 - 758
  • [42] Single-Agent Ibrutinib Demonstrates Efficacy and Safety in Patients with Relapsed/Refractory Marginal Zone Lymphoma: A Multicenter, Open-Label, Phase 2 Study
    Noy, Ariela
    de Vos, Sven
    Thieblemont, Catherine
    Martin, Peter
    Flowers, Christopher
    Morschhauser, Franck
    Collins, Graham P.
    Ma, Shuo
    Coleman, Morton
    Peles, Shachar
    Smith, Stephen
    Smith, Alina
    Munneke, Brian
    Dimery, Isaiah
    Beaupre, Darrin
    Chen, Robert W.
    BLOOD, 2016, 128 (22)
  • [43] Umbralisib monotherapy demonstrates efficacy and safety in patients with relapsed/refractory marginal zone lymphoma: A multicenter, open-label, registration directed Phase II study
    Fowler, Nathan H.
    Samaniego, Felipe
    Jurczak, Wojciech
    Lech-Maranda, Ewa
    Ghosh, Nilanjan
    Anz, Bertrand
    Patten, Piers
    Reeves, James A.
    Leslie, Lori A.
    Smolewski, Piotr
    Chavez, Julio C.
    Ghia, Paolo
    Tarella, Corrado
    Burke, John M.
    Sharman, Jeff
    Kolibaba, Kathryn
    O'Connor, Owen A.
    Cheah, Chan Y.
    Miskin, Hari P.
    Sportelli, Peter
    Weiss, Michael S.
    Zinzani, Pier Luigi
    CANCER RESEARCH, 2019, 79 (13)
  • [44] Umbralisib monotherapy demonstrates efficacy and safety in patients with relapsed/refractory marginal zone lymphoma: A multicenter, open label, registration directed phase II study.
    Fowler, Nathan Hale
    Samaniego, Felipe
    Jurczak, Wojciech
    Lech-Maranda, Ewa
    Ghosh, Nilanjan
    Patten, Piers
    Reeves, James Andrew
    Leslie, Lori Ann
    Chavez, Julio C.
    Ghia, Paolo
    Tarella, Corrado
    Burke, John M.
    Sharman, Jeff Porter
    Kolibaba, Kathryn
    O'Connor, Owen A.
    Cheah, Chan
    Miskin, Hari P.
    Sportelli, Peter
    Weiss, Michael S.
    Zinzani, Pier Luigi
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [45] Long-term efficacy of the combination of lenalidomide and rituximab in elderly relapsed/refractory diffuse large B-cell lymphoma patients
    Zinzani, Pier Luigi
    Pellegrini, Cinzia
    Derenzini, Enrico
    Argnani, Lisa
    Pileri, Stefano
    HEMATOLOGICAL ONCOLOGY, 2013, 31 (04) : 223 - 224
  • [46] Long-term efficacy in patients with relapsed/refractory diffuse large B-cell lymphoma achieving a complete response with pixantrone
    Cencini, Emanuele
    Rocco, Melania
    Ghio, Francesco
    Simonetti, Federico
    Cuccaro, Annarosa
    De Marco, Federica
    Consoli, Chiara
    Bocchia, Monica
    Fabbri, Alberto
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2023, 111 (02) : 247 - 253
  • [47] Long-Term Safety and Efficacy of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter, Open-Label, Phase II Study
    Song, Yuqin
    Song, Yongping
    Liu, Lihong
    Zhang, Mingzhi
    Li, Zhiming
    Ji, Chunyan
    Xu, Wei
    Liu, Ting
    Xu, Bing
    Wang, Xin
    Gao, Sujun
    Zhang, Huilai
    Hu, Yu
    Li, Yan
    Cheng, Ying
    Yang, Haiyan
    Cao, Junning
    Zhu, Zunmin
    Hu, Jianda
    Zhang, Wei
    Jing, Hongmei
    Ding, Kaiyang
    Lu, Zhengguang
    Zhang, Bin
    Zhao, Renbin
    Xu, Zhixin
    Zhu, Jun
    BLOOD, 2020, 136
  • [48] Long-Term Follow-up of Idelalisib Monotherapy in Patients with Double-Refractory Marginal Zone Lymphoma or Lymphoplasmacytic Lymphoma/Waldenstrom's Macroglobulinemia
    Wagner-Johnston, Nina D.
    Schuster, Stephen J.
    de Vos, Sven
    Salles, Gilles A.
    Jurczak, Wojciech
    Rajakumaraswamy, Nishan
    Xing, Guan
    Gopal, Ajay K.
    BLOOD, 2019, 134
  • [49] Efficacy and safety of ibrutinib in Japanese patients with relapsed or refractory mantle cell lymphoma
    Maruyama, Dai
    Nagai, Hirokazu
    Fukuhara, Noriko
    Kitano, Toshiyuki
    Ishikawa, Takayuki
    Shibayama, Hirohiko
    Choi, Ilseung
    Hatake, Kiyohiko
    Uchida, Toshiki
    Nishikori, Momoko
    Kinoshita, Tomohiro
    Matsuno, Yoshihiro
    Nishikawa, Tomoaki
    Takahara, Satoko
    Tobinai, Kensei
    CANCER SCIENCE, 2016, 107 (12) : 1785 - 1790
  • [50] The MAGNOLIA Trial: Zanubrutinib, a Next-Generation Bruton Tyrosine Kinase Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Marginal Zone Lymphoma
    Opat, Stephen
    Tedeschi, Alessandra
    Linton, Kim
    McKay, Pamela
    Hu, Bei
    Chan, Henry
    Jin, Jie
    Sobieraj-Teague, Magdalena
    Zinzani, Pier Luigi
    Coleman, Morton
    Thieblemont, Catherine
    Browett, Peter
    Ke, Xiaoyan
    Sun, Mingyuan
    Marcus, Robert
    Portell, Craig A.
    Ardeshna, Kirit
    Bijou, Fontanet
    Walker, Patricia
    Hawkes, Eliza A.
    Mapp, Sally
    Ho, Shir-Jing
    Talaulikar, Dipti
    Zhou, Ke-Shu
    Co, Melannie
    Li, Xiaotong
    Zhou, Wenxiao
    Cappellini, Massimo
    Tankersley, Chris
    Huang, Jane
    Trotman, Judith
    CLINICAL CANCER RESEARCH, 2021, 27 (23) : 6323 - 6332