Impregnation of Ultra-High-Density Polyethylene with Unsymmetrical Disulfides in Subcritical Freon Media

被引:5
|
作者
Zalepugin, D. Yu [1 ]
Maksimkin, A. V. [2 ]
Kiselevsky, M. V. [2 ,3 ]
Tilkunova, N. A. [1 ]
Anisimova, N. Yu [2 ,3 ]
Chernyshova, I. V. [1 ]
Spirina, T. S. [3 ]
Senatov, F. S. [3 ]
Vlasov, M. I. [1 ]
机构
[1] State Plant Med Drugs, Moscow 111024, Russia
[2] Natl Univ Sci & Technol MISIS, Moscow 119049, Russia
[3] Minist Hlth Russian Federat, Blokhin Russian Canc Res Ctr, Moscow 115478, Russia
关键词
subcritical freons; impregnation; ultra-high-density polyethylene; implants; SUPERCRITICAL CARBON-DIOXIDE; FLUID TECHNOLOGY; POTENTIAL BIOCIDES; EXTRACTION; COMPONENTS; FILMS; SCAFFOLDS; IMPLANTS;
D O I
10.1134/S1990793117070223
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
For the first time, ultra-high-density polyethylene (UHDPE) samples impregnated with antibacterial unsymmetrical disulfides (allyl benzothiazol-2-yl disulfide and allyl 8-quinolyl disulfide) were obtained in subcritical freon R22 in the absence of organic solvents as modifiers. Freon R22 was completely removed from the impregnated samples that provided a high purity of the final material. Potential implants based on the UHDPE impregnated with unsymmetrical disulfides were shown to manifest antibacterial and antifungal activity.
引用
收藏
页码:1173 / 1179
页数:7
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