Apraxia of eyelid opening after subthalamic deep brain stimulation may be caused by reduction of levodopa

被引：19
|
作者：
Umemura, Atsushi [1 ]
Toyoda, Takanari [2 ]
Yamamoto, Kenichi [1 ]
Oka, Yuichi [1 ]
Ishii, Fumiyasu [3 ]
Yamada, Kazuo [1 ]
机构：
[1] Nagoya City Univ, Sch Med, Dept Neurosurg, Mizuho Ku, Aichi 4678601, Japan
[2] Nagoya City Univ, Sch Med, Dept Neurol, Mizuho Ku, Aichi 4678601, Japan
[3] Nagoya City Univ, Sch Med, Dept Rehabil Med, Mizuho Ku, Aichi 4678601, Japan
来源：
PARKINSONISM & RELATED DISORDERS | 2008年 / 14卷 / 08期
关键词：
Apraxia of eyelid opening; Parkinson's disease; Deep brain stimulation; Subthalamic nucleus; Levodopa;
D O I：
10.1016/j.parkreldis.2007.12.008
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Apraxia of eyelid opening (ALO) is an infrequent side effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson's disease (PD). However, the pathogenesis of ALO after STN DBS is not well understood. We report on two patients who suffered from disabling ALO after bilateral STN DBS. Their ALO improved by resuming the levodopa medication that had been discontinued after the surgery. Although ALO after STN DBS is considered as an adverse effect of STN stimulation, postoperative modification of dopaminergic medication may be a cause of ALO after STN DBS. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：655 / 657
页数：3
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