The relevance of the article is due to Turkmenistan's important place among Ukrainian foreign trade partners and Ukraine's desire to develop comprehensive relations with this Central Asian country, that have recently been driven by negative trends. It is a recent problem for Ukraine as a country affected by geopolitical risks. The purpose of the article is to highlight the problems of foreign trade relations between Ukraine and Turkmenistan and to identify promising directions to overcome them. The research methodology is presented by methods of theoretical generalization, analysis and synthesis, systematic and integrated approach. The national interests of Ukraine and Turkmenistan in bilateral trade cooperation are revealed in the research. Natural gas is of paramount importance in foreign trade relations between the countries. Perspective directions of foreign trade relations are identified, that are connected with the increase of mutual trade volumes and diversification of cooperation directions in energy and non-energy spheres.