Electrochemical Determination of Phenylephrine Hydrochloride Based on Graphene-TiO2 Modified Glassy Carbon Electrode

被引：0
|
作者：
Li, Kang [1 ]
Zhu, Mingfang [1 ]
Zhang, Hongwu [1 ]
Zhao, Jie [2 ]
机构：
[1] Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou, Guangdong, Peoples R China
[2] Guangdong Pharmaceut Univ, Sch Hlth Sci, Guangzhou, Guangdong, Peoples R China
来源：
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2013年 / 8卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Phenylephrine Hydrochloride; Electrochemistry; Determination; OXIDE;
D O I：
暂无
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
A novel voltammetric sensor based on TiO2 nanoparticles and graphene composite (GR/TiO2) was developed. The nanocomposite modified glassy carbon electrode was characterized using scanning electron microscope (SEM). The electrochemical behavior of phenylephrine hydrochloride (PHE) was investigated on this sensor. The results indicated that the GR/TiO2 modified electrode exhibited efficient electrocatalytic oxidation for PHE with about 2.87 times higher current response. Using differential pulse voltammetry (DPV), the GR/TiO2 modified electrode exhibited a linear voltammetric response for PHE in the concentration range of 5.0x10(-7)-2.0x10(-5) mol L-1, with the limit of detection (LOD) of 2.0 x 10(-7) mol L-1 (S/N= 3). The sensor was applied to determine PHE in urine and human serum samples were studied.
引用
收藏
页码：4047 / 4054
页数：8
相关论文
共 50 条
  • [31] VOLTAMMETRIC DETERMINATION OF RUPATADINE AT GRAPHENE MODIFIED GLASSY CARBON ELECTRODE
    Devnani, H.
    Singh, P.
    Saxena, S.
    Satsangee, S. P.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2014, 5 (11):
  • [32] Voltammetric Determination of Bergenin with Graphene Modified Glassy Carbon Electrode
    Li, Xiaobao
    Zou, Ruyi
    Niu, Yanyan
    Shao, Taiming
    Chen, Yong
    Sun, Wei
    He, Mengxiong
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2018, 13 (02): : 1976 - 1984
  • [33] Electrochemical Determination of Phoxim in Food Samples Employing a Graphene-Modified Glassy Carbon Electrode
    Chao, Mingyong
    Chen, Meifeng
    FOOD ANALYTICAL METHODS, 2014, 7 (09) : 1729 - 1736
  • [34] Study and Electrochemical Determination of Tyrosine at Graphene Nanosheets Composite Film Modified Glassy Carbon Electrode
    Behpour, M.
    Masoum, S.
    Meshki, M.
    JOURNAL OF NANOSTRUCTURES, 2013, 3 (02) : 243 - 251
  • [35] Electrochemical Determination of Tyrosine Using Graphene and Gold Nanoparticle Composite Modified Glassy Carbon Electrode
    Liu, M.
    Lao, J.
    Wang, H.
    Xu, Z.
    Li, J.
    Wen, L.
    Yin, Z.
    Luo, C.
    Peng, H.
    RUSSIAN JOURNAL OF ELECTROCHEMISTRY, 2021, 57 (01) : 41 - 50
  • [36] Electrochemical Determination of Phoxim in Food Samples Employing a Graphene-Modified Glassy Carbon Electrode
    Mingyong Chao
    Meifeng Chen
    Food Analytical Methods, 2014, 7 : 1729 - 1736
  • [37] Methyldopa electrochemical sensor based on a glassy carbon electrode modified with Cu/TiO2 nanocomposite
    Tajik, Somayeh
    Beitollahi, Hadi
    Biparva, Pourya
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2018, 83 (7-8) : 863 - 874
  • [38] Electrochemical Determination of Tyrosine Using Graphene and Gold Nanoparticle Composite Modified Glassy Carbon Electrode
    M. Liu
    J. Lao
    H. Wang
    Z. Xu
    J. Li
    L. Wen
    Z. Yin
    C. Luo
    H. Peng
    Russian Journal of Electrochemistry, 2021, 57 : 41 - 50
  • [39] Electrochemical sensor for epinephrine based on a glassy carbon electrode modified with graphene/gold nanocomposites
    Cui, Fei
    Zhang, Xiaoli
    JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2012, 669 : 35 - 41
  • [40] The electrochemical sensor based on electrochemical oxidation of nitrite on metalloporphyrin-graphene modified glassy carbon electrode
    Li, C.
    Guo, B.
    Guo, X. M.
    Wang, F.
    RSC ADVANCES, 2016, 6 (93): : 90480 - 90488
12345