Cardiac dysfunction and N-terminal pro-B-type natriuretic peptide in exacerbations of chronic obstructive pulmonary disease

被引：17
|
作者：
Lee, M. H. S. [1 ,2 ]
Chang, C. L. [1 ]
Davies, A. R. [1 ]
Davis, M. [2 ]
Hancox, R. J. [1 ,3 ]
机构：
[1] Waikato Hosp, Resp Res Unit, Dept Resp Med, Hamilton, New Zealand
[2] Waikato Hosp, Dept Cardiol, Hamilton, New Zealand
[3] Univ Otago, Dept Prevent & Social Med, Dunedin, New Zealand
来源：
INTERNAL MEDICINE JOURNAL | 2013年 / 43卷 / 05期
关键词：
COPD; heart failure; BNP; NT-proBNP; echocardiography; TAPSE; ECHOCARDIOGRAPHIC-ASSESSMENT; VENTRICULAR DYSFUNCTION; COR-PULMONALE; COPD; MORTALITY; HEART;
D O I：
10.1111/imj.12112
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Elevated levels of B-type natriuretic peptides among patients with exacerbations of chronic obstructive pulmonary disease (COPD) are associated with higher mortality. The pathophysiology is unclear. To establish if elevated levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) are due to right or left heart dysfunction, we performed echocardiograms in 18 patients admitted to hospital with COPD. Elevated levels of NT-proBNP were associated with both right and left heart dysfunction and indicate that these patients have biventricular dysfunction rather than isolated right ventricular compromise.
引用
收藏
页码：595 / 598
页数：4
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