Selenium-Directed ortho-C-H Borylation by Iridium Catalysis

被引：12

作者：

Tang, Jia ^{[1
]}

Singh, Thishana ^{[2
]}

Li, Xingzhen ^{[1
]}

Liu, Linpeng ^{[1
]}

Zhou, Taigang ^{[1
,3
]}

机构：

[1] Southwest Petr Univ, Coll Chem & Chem Engn, Chengdu 610500, Sichuan, Peoples R China

[2] Univ KwaZulu Natal, Coll Agr Engn & Sci, Sch Chem & Phys, ZA-4000 Durban, South Africa

[3] Southwest Petr Univ, State Key Lab Oil & Gas Reservoir Geol & Exploita, Chengdu 610500, Sichuan, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 18期

基金：

中国国家自然科学基金;

关键词：

BONDS; ORGANOSELENIUM; ARENES;

D O I：

10.1021/acs.joc.0c01559

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An iridium-catalyzed selenium-directed ortho-C-H borylation of benzyl selenide derivatives was successfully developed. This is the first example where selenium is used as a directing group in C-H borylation. The reaction was carried out using the tricyclohexylphosphine ligand for an improved catalytic efficiency. Various substrates were tolerated and afforded either ortho-monoborylated products (substrates bearing ortho- or meta-substituents) or diborylated products (substrates bearing parasubstituents) in good yields. This study provides an efficient synthetic method for the preparation of a variety of organo-selenium compounds.

引用

页码：11959 / 11967

页数：9

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