Stellaria media (L.) Vill.- A plant with immense therapeutic potentials: phytochemistry and pharmacology

被引:27
|
作者
Oladeji, Oluwole Solomon [1 ]
Oyebamiji, Abel Kolawole [2 ,3 ]
机构
[1] Landmark Univ, Nat Prod Res Unit, Dept Phys Sci, Ind Chem Programme,Coll Pure & Appl Sci, PMB 1001, Omu Aran, Nigeria
[2] Adeleke Univ, Dept Basic Sci, Fac Sci, Ede, Nigeria
[3] Ladoke Akintola Univ Technol, Dept Pure & Appl Chem, Ogbomosho, Nigeria
关键词
Stellaria media; Caryophyllaceae; Ethnopharmacological; Phytochemistry; Biological activities; Plant biology; Pharmaceutical science; Biochemistry; Pharmacology; Evidence-based medicine; ALPHA-AMYLASE; ANTIOXIDANT ACTIVITIES; MEDICINAL-PLANTS; EXTRACT; CONSTITUENTS; SAPONINS; GRADIENT; REMEDIES; TANNINS; MOENCH;
D O I
10.1016/j.heliyon.2020.e04150
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Stellaria media Vill. is a representative of Caryophyllaceae family. The plant is widely dispersed all over the world and has been used as therapeutic substance since time immemorial. This review is aimed at exploring the chemical constituents and pharmacological activities of S. media. The findings revealed important secondary metabolites such as flavonoid, oligosaccharide stellariose, anthraquinone derivatives, fatty acid, steroid saponins and phenolic compounds. These bioactive metabolites displayed divers pharmacological activities such as antiobesity, antifungal, antibacterial, antioxidant, anti-proliferative, anti-inflammatory, analgesic, antidiabetic and anxiolytic activities. All findings revealed that S. media is a major sped of Caryophyllaceae family. ever, bioactive constituents and pharmacological potential of are not well appraised. Hence, extracts with established pharmacological activities should be subjected to bioassay guided isolation so as to obtain compounds with novel structural moieties prior to toxicogenetic appraisals.
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页数:7
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