Pulmonary complications of infliximab therapy in patients with rheumatoid arthritis

被引：0
|
作者：
Östör, AJK
Chilvers, ER
Somerville, MF
Lim, AYN
Lane, SE
Crisp, AJ
Scott, DGI
机构：
[1] Addenbrookes Hosp, Dept Rheumatol, Cambridge CB2 2QQ, England
[2] Norfolk & Norwich Univ Hosp, Dept Rheumatol, Norwich, Norfolk, England
[3] Univ Cambridge, Addenbrookes Hosp, Div Resp Med, Dept Med,Sch Clin Med, Cambridge CB2 2QQ, England
[4] Papworth Hosp, Cambridge CB3 8RE, England
来源：
JOURNAL OF RHEUMATOLOGY | 2006年 / 33卷 / 03期
关键词：
rheumatoid arthritis; interstitial lung disease; infliximab; anti-tumor necrosis factor-alpha therapy; usual interstitial pneumonia; bronchiolitis obliterans organizing pneumonia;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We describe 5 patients with rheumatoid arthritis (RA) who developed pulmonary complications following infliximab therapy; 4 patients had preexisting usual interstitial pneumonia. As the pathophysiology of the pulmonary insult is unknown, we advise caution in the use of anti-tumor necrosis factor-alpha therapy in patients with RA with underlying lung disease of sufficient severity to withhold methotrexate treatment.
引用
收藏
页码：622 / 628
页数：7
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