Investigation of a Lomentospora prolificans case cluster with whole genome sequencing

被引：8

作者：

Boan, Peter ^{[1
,2
]}

Pang, Stanley ^{[3
]}

Gardam, Dianne J. ^{[2
]}

Darragh, Helen ^{[2
]}

Wright, Matthew ^{[1
,2
]}

Coombs, Geoffrey W. ^{[2
,3
]}

机构：

[1] Fiona Stanley Hosp, 11 Robin Warren Ave, Perth, WA 6150, Australia

[2] PathWest Lab Med WA, 11 Robin Warren Ave, Perth, WA 6150, Australia

[3] Murdoch Univ, 90 South St, Perth, WA 6150, Australia

来源：

MEDICAL MYCOLOGY CASE REPORTS | 2020年 / 29卷

关键词：

Lomentospora prolificans; Scedosporium prolificans; Fungal outbreak; Whole genome sequencing; Antifungal resistance; SCEDOSPORIUM; MILTEFOSINE; VORICONAZOLE; COMBINATION; INFECTION; OUTBREAK;

D O I：

10.1016/j.mmcr.2020.05.003

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates from unrelated infections at Hospital 2., showing a high number of mutational differences (> 10,000 single nucleotide polymorphisms) between L. prolificans isolates from Hospital 1. Novel typing of isolates by WGS did not demonstrate a single causative strain.

引用

页码：1 / 4

页数：4

共 50 条

[11] A case of Lomentospora prolificans endophthalmitis treated with the novel antifungal agent Olorofim
Michael Dong
Fiona Pearce
Nandini Singh
Ming-Lee Lin
Journal of Ophthalmic Inflammation and Infection, 14
[12] Azacitidine/posaconazole/venetoclaxLack of efficacy and disseminated lomentospora prolificans infection: case report
Reactions Weekly, 2024, 2035 (1) : 95 - 95
[13] The use of whole-genome sequencing in cluster investigation of a multidrug-resistant tuberculosis outbreak
Lalor, Maeve K.
Casali, Nicola
Walker, Timothy M.
Anderson, Laura F.
Davidson, Jennifer A.
Ratna, Natasha
Mullarkey, Cathy
Gent, Mike
Foster, Kirsty
Brown, Tim
Magee, John
Barrett, Anne
Crook, Derrick W.
Drobniewski, Francis
Thomas, H. Lucy
Abubakar, Ibrahim
EUROPEAN RESPIRATORY JOURNAL, 2018, 51 (06)
[14] CHARACTERIZATION OF A CLUSTER OF DISSEMINATED GONOCOCCAL INFECTIONS IN ONE CALIFORNIA COUNTY USING CLINICAL DATA, CASE INVESTIGATION, AND WHOLE GENOME SEQUENCING
Scott, Karen
Kozyreva, Varvara
Chaturvedi, Vishnu
Beebe, James
Bauer, Heidi
Stoltey, Julie
SEXUALLY TRANSMITTED DISEASES, 2016, 43 : S126 - S127
[15] Costs associated with invasive Scedosporium and Lomentospora prolificans infections: a case-control study
Neoh, Chin Fen
Chen, Sharon C. A.
Kong, David C. M.
Hamilton, Kate
Nguyen, Quoc A.
Spelman, Tim
Tew, Michelle
Harvey, Emma L.
Ho, Su Ann
Saunders, Natalie R.
Tennakoon, Surekha
Crowe, Amy
Marriott, Debbie
Trubiano, Jason A.
Slavin, Monica A.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2024, 79 (01) : 46 - 54
[16] report Disseminated Lomentospora prolificans infection that could have been predicted: A case report
Sato, Koga
Hayashi, Toshimasa
Ishizaki, Takuma
Yoshida, Masakazu
Watanabe, Akira
IDCASES, 2024, 37
[17] Pulmonary scedosporiosis caused by Lomentospora prolificans in a patient who is immunocompetent: A rare case report
Xing, Xiqian
Liu, Qian
Yuan, Wenli
Zhu, Chenshao
Yang, Jiao
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2023, 130 : 208 - 210
[18] Whole Exome Sequencing and Whole Genome Sequencing for Investigation of the Genetic Basis of Obesity: A Rapid Review
Dehghan, Roghayeh
Salehi, Mansoor
BAHRAIN MEDICAL BULLETIN, 2023, 45 (02) : 1492 - 1497
[19] A first case report of vertebral osteomyelitis with epidural abscess caused by Lomentospora prolificans in an immunocompetent woman
Jitmuang, A.
Wangchinda, W. W.
Chongtrakool, P.
MYCOSES, 2017, 60 : 123 - 124
[20] A case of NBAS validated by Whole Genome Sequencing.
Sleutels, Frank
Demirdas, S.
Oussoren, Esmee
Hoefsloot, Lies
EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 1026 - 1027

← 1 2 3 4 5 →