Aspirin in the primary prevention of colorectal cancer

被引:0
|
作者
Fernandez-Calderon, M. [1 ]
Betes Ibanez, M. T. [1 ]
机构
[1] Univ Navarra Clin, Dept Digest, Pamplona 31008, Spain
关键词
Aspirin; Colorectal cancer; Prevention; FAMILIAL ADENOMATOUS POLYPOSIS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; RANDOMIZED-TRIALS; CYCLOOXYGENASE-2; INHIBITOR; FOLLOW-UP; RISK; CHEMOPREVENTION; METAANALYSIS; RECURRENCE; CELECOXIB;
D O I
10.4321/S1137-66272012000200008
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with a reduction in the risk of developing adenomas and colorectal cancer. The available scientific evidence justifies the need for more studies that evaluate the protective effect of aspirin and other NSAIDs as a preventive measure against cancer of the colon; define the minimum efficient dosage; the age at which to begin treatment; the most convenient duration of the latter; and the sub-populations for which the benefits of chemoprophylaxis outweigh possible adverse effects.
引用
收藏
页码:261 / 267
页数:7
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