Sesquiterpenes from the Vietnamese Marine Sponge Dysidea fragilis

被引：1

作者：

Nguyen Thi Cue ^{[1
]}

Hoang Le Tuan Anh ^{[1
]}

Dan Thi Thuy Hang ^{[1
]}

Nguyen Xuan Nhiem ^{[1
]}

Nguyen Hai Dang ^{[1
]}

Nguyen Hoai Nam ^{[1
]}

Pham Hai Yen ^{[1
]}

Do Cong Thung ^{[2
]}

Vu Kim Thu ^{[3
]}

Chau Van Minh ^{[1
]}

Phan Van Kiem ^{[1
]}

机构：

[1] VAST, Inst Marine Biochem, Hanoi, Vietnam

[2] VAST, Inst Marine Environm & Resources, Ngo Quyen, Haiphong, Vietnam

[3] Hanoi Univ Min & Geol, Fac Basic Sci, Hanoi, Vietnam

来源：

NATURAL PRODUCT COMMUNICATIONS | 2015年 / 10卷 / 08期

关键词：

Dysidea fragilis; Dysideidae; Dysinidin A; Dysinidin B; Sesquiterpene;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new sesquiterpenes, named dysinidins A-B (3, 4) along with two known sesquiterpenes, furodysinin lactone (1) and O-methyl furodysinin lactone (2), were isolated from the Vietnamese marine sponge Dysidea fragilis. Their structures were determined by 1D- and 2D-NMR spectroscopies and HR ESI MS, as well as by comparison with reported literature data. None of compounds showed inhibitory growth of human lung cancer cell lines, A-549 and H-1975 (IC50 > 30 mu M).

引用

页码：1341 / 1342

页数：2

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