Gabapentin as an adjunctive treatment in bipolar disorder

被引：0

作者：

Young, LT ^{[1
]}

Robb, JC

Hasey, GM

MacQueen, GM

Siotis, IP

Marriott, M

Joffe, RT

机构：

[1] McMaster Univ, Mood Disorder Program, Hamilton, ON, Canada

[2] McMaster Univ, Dept Psychiat, Hamilton, ON, Canada

来源：

JOURNAL OF AFFECTIVE DISORDERS | 1999年 / 55卷 / 01期

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D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: To evaluate the efficacy of gabapentin as an adjunctive treatment for bipolar disorder in both depressed and manic phases. Method: Thirty seven patients with bipolar type I or II with or without a rapid cycling course were openly treated with gabapentin added to current treatment for up to six months. Mood symptoms were rated weekly for 12 weeks then monthly for 3 months utilizing the HamD and YMS. Results: Participants experienced a significant reduction in both depressive and manic symptoms. Conclusions: These findings are consistent with others in establishing the efficacy of,gabapentin in both phases of bipolar disorder. Limitations: Small sample size and the use of an open uncontrolled design limit interpretation of results. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：73 / 77

页数：5

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