Randomized, Double Blinded, Placebo-Controlled, Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease

被引：0
|
作者：
Rosas, I. [1 ]
Solomon, J. [2 ]
Donoff, S. [3 ]
Woodhead, F. [4 ]
Raghu, G. [5 ]
Hilary, G. [6 ]
机构：
[1] Baylor Coll Med, Houston, TX 77030 USA
[2] Univ Colorado, Denver, CO 80202 USA
[3] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA
[4] Univ Leicester, Leicester, Leics, England
[5] Univ Washington, Seattle, WA 98195 USA
[6] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[7] TRAIL NETWORK, Seattle, WA USA
来源：
EUROPEAN RESPIRATORY JOURNAL | 2022年 / 60卷
关键词：
D O I：
10.1183/13993003.congress-2022.4534
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
4534
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Evaluation of the safety, tolerability, and efficacy of pimavanserin versus placebo in patients with Alzheimer's disease psychosis: a phase 2, randomised, placebo-controlled, double-blind study
    Ballard, Clive
    Banister, Carol
    Khan, Zunera
    Cummings, Jeffrey
    Demos, George
    Coate, Bruce
    Youakim, James M.
    Owen, Randall
    Stankovic, Srdjan
    LANCET NEUROLOGY, 2018, 17 (03): : 213 - 222
  • [32] Efficacy and Safety of Tangshen Formula on Patients with Type 2 Diabetic Kidney Disease: A Multicenter Double-Blinded Randomized Placebo-Controlled Trial
    Li, Ping
    Chen, Yiping
    Liu, Jianping
    Hong, Jing
    Deng, Yueyi
    Yang, Fang
    Jin, Xiuping
    Gao, Jing
    Li, Jing
    Fang, Hui
    Liu, Geling
    Shi, Liping
    Du, Jinhang
    Li, Yang
    Yan, Meihua
    Wen, Yumin
    Yang, Wenying
    PLOS ONE, 2015, 10 (05):
  • [33] A randomized, double-blind, placebo-controlled phase 2 study to assess safety, tolerability, and efficacy of RT001 in patients with amyotrophic lateral sclerosis
    Weemering, Daphne N.
    Midei, Mark
    Milner, Peter
    Gopalakrishnan, Vidhya
    Kumar, Anil
    Dannenberg, Andrew J.
    Bunte, Tommy M.
    Foucher, Juliette
    Ingre, Caroline
    Kenina, Viktorija
    Rallmann, Karin
    van den Berg, Leonard H.
    van Eijk, Ruben P. A.
    EUROPEAN JOURNAL OF NEUROLOGY, 2023, 30 (12) : 3722 - 3731
  • [34] A Randomized Placebo-Controlled Phase 2 Study To Evaluate Efficacy, Safety and Tolerability Of Two Secukinumab Loading Dose Regimens In Subjects With Active Rheumatoid Arthritis Despite Treatment With Methotrexate
    Adami, Silvano
    Beaulieu, Andre
    Rahman, Proton
    Seriolo, Bruno
    Lee, Janet S.
    Krammer, Gerhard
    Porter, Brian
    Thulasiraman, Anuradha
    Richards, Hanno B.
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S220 - S220
  • [35] Safety and tolerability of KarXT (xanomeline-trospium) in a phase 2, randomized, double-blind, placebo-controlled study in patients with schizophrenia
    Correll, Christoph U.
    Angelov, Angel S.
    Miller, Andrew C.
    Weiden, Peter J.
    Brannan, Stephen K.
    SCHIZOPHRENIA, 2022, 8 (01)
  • [36] Efficacy and Safety of Omilancor in a Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Crohn's Disease
    Chowla, Navreet M.
    Tariq, Raseen
    Aggarwal, Manik
    Loftus, Edward V.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (10): : S820 - S821
  • [37] Safety, tolerability, and efficacy of intranasally-administered detoxified LTh(αK) in mild-to-moderate COVID-19 patients: A randomized, double-blinded, placebo-controlled phase 2 study
    Cheng, Chien-Yu
    Su, Ying-Shih
    Chen, Chyi-Liang
    Chang, Mingi
    Huang, Shu-Wei
    Huang, Peng-Nien
    Shih, Shin-Ru
    Hsu, Yu-Shen
    Chiu, Cheng-Hsun
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2024, 20 (01)
  • [38] Pirfenidone in patients with unclassifiable progressive fibrosing interstitial lung disease: design of a double-blind, randomised, placebo-controlled phase II trial
    Maher, Toby M.
    Corte, Tamera J.
    Fischer, Aryeh
    Kreuter, Michael
    Lederer, David J.
    Molina-Molina, Maria
    Axmann, Judit
    Kirchgaessler, Klaus-Uwe
    Cottin, Vincent
    BMJ OPEN RESPIRATORY RESEARCH, 2018, 5 (01):
  • [39] Efficacy and safety of guselkumab in patients with active psoriatic arthritis: a randomised, double-blind, placebo-controlled, phase 2 study
    Deodhar, Atul
    Gottlieb, Alice B.
    Boehncke, Wolf-Henning
    Dong, Bin
    Wang, Yuhua
    Zhuang, Yanli
    Barchuk, William
    Xu, Xie L.
    Hsia, Elizabeth C.
    LANCET, 2018, 391 (10136): : 2213 - 2224
  • [40] Safety and Efficacy of Poseltinib, Bruton's Tyrosine Kinase Inhibitor, in Patients With Rheumatoid Arthritis: A Randomized, Double-blind, Placebo-controlled, 2-part Phase II Study
    Genovese, Mark C.
    Spindler, Alberto
    Sagawa, Akira
    Park, Won
    Dudek, Anna
    Kivitz, Alan
    Chao, Jeannie
    Chan, Lai Shan Melanie
    Witcher, Jennifer
    Barchuk, William
    Nirula, Ajay
    JOURNAL OF RHEUMATOLOGY, 2021, 48 (07) : 969 - 976
12345