Spread of Multidrug-Resistant Pseudomonas aeruginosa Clones in a University Hospital

被引：37
|
作者：
Koutsogiannou, Maria [1 ]
Drougka, Eleanna [1 ]
Liakopoulos, Apostolos [2 ]
Jelastopulu, Eleni [3 ]
Petinaki, Efthimia [2 ]
Anastassiou, Evangelos D. [1 ]
Spiliopoulou, Iris [1 ]
Christofidou, Myrto [1 ]
机构：
[1] Univ Patras, Sch Med, Dept Microbiol, GR-26110 Patras, Greece
[2] Univ Thessalia, Sch Med, Dept Microbiol, Larisa, Greece
[3] Univ Patras, Sch Med, Dept Publ Hlth, GR-26110 Patras, Greece
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 02期
关键词：
METALLO-BETA-LACTAMASE; OUTBREAK; INFECTIONS; VIM-2; SECRETION; VIRULENCE; STRAINS; CROATIA; TOXINS; GENE;
D O I：
10.1128/JCM.03071-12
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
An outbreak of multidrug-resistant Pseudomonas aeruginosa (MDRPA) infections in a university hospital is described. Phenotypic and genotypic analysis of 240 isolates revealed that 152 patients, mainly in the intensive care unit (ICU), were colonized or infected with MDRPA, the majority with O11. All metallo-beta-lactamase (MBL)-positive isolates carried the bla(VIM-2) or bla(VIM-1) gene. One or more type III secretion system toxin genes were detected in most isolates. Five dominant pulsed-field gel electrophoresis (PFGE) types were characterized, associated with ST235, ST111, ST253, ST309, and ST639.
引用
收藏
页码：665 / 668
页数：4
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