Toll-like receptor 9 is alternatively cleaved to generate a soluble form of the receptor that downregulates response to CpG-DNA

被引：0
|
作者：
Chockalingam, Annapoorani [1 ]
Brooks, James [1 ]
Cameron, Jody [1 ]
Leifer, Cynthia [1 ]
机构：
[1] Cornell Univ, Microbiol & Immunol, Ithaca, NY USA
来源：
JOURNAL OF IMMUNOLOGY | 2010年 / 184卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
136.25
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Toll-like receptor 9 interaction with CpG ODN - An in silico analysis approach
    Zhou, Wei
    Li, Yan
    Pan, Xichun
    Gao, Yuan
    Li, Beiping
    Qiu, Zhengliang
    Liang, Long
    Zhou, Hong
    Yue, Junjie
    THEORETICAL BIOLOGY AND MEDICAL MODELLING, 2013, 10
  • [32] Equilibrium Binding Model for CpG DNA-Dependent Dimerization of Toll-like Receptor 9 Ectodomain
    Reikine, Stephanie
    McLaughlin, Stephen H.
    Modis, Yorgo
    BIOCHEMISTRY, 2020, 59 (43) : 4155 - 4162
  • [33] Cross talk between Leishmania donovani CpG DNA and Toll-like receptor 9: An immunoinformatics approach
    Gupta, Chhedi Lal
    Akhtar, Salman
    Waye, Andrew
    Pandey, Nihar R.
    Pathak, Neelam
    Bajpai, Preeti
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 459 (03) : 424 - 429
  • [34] The sweetness of the DNA backbone drives Toll-like receptor 9
    Wagner, Hermann
    CURRENT OPINION IN IMMUNOLOGY, 2008, 20 (04) : 396 - 400
  • [35] In Vitro and In Vivo Stimulation of Toll-Like Receptor 9 by CpG Oligodeoxynucleotides Incorporated Into Polypod-Like DNA Nanostructures
    Takahashi, Yosuke
    Maezawa, Tatsuoki
    Araie, Yuki
    Takahashi, Yuki
    Takakura, Yoshinobu
    Nishikawa, Makiya
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 106 (09) : 2457 - 2462
  • [36] Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    Ahmad-Nejad, P
    Häcker, H
    Rutz, M
    Bauer, S
    Vabulas, RM
    Wagner, H
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2002, 32 (07) : 1958 - 1968
  • [37] HYPERINSULINAEMIA DOWNREGULATES TOLL-LIKE RECEPTOR 4 IN THE EQUINE HEART
    de Laat, M. A.
    Gruntmeir, K. J.
    Pollitt, C. C.
    Sillence, M. N.
    McGowan, C. M.
    Lacombe, V. A.
    JOURNAL OF VETERINARY INTERNAL MEDICINE, 2013, 27 (03) : 655 - 655
  • [38] Toll-like receptors involved in the response to microbial pathogens: Development of agonists for toll-like receptor 9
    Schetter, C
    Vollmer, J
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2004, 7 (02) : 204 - 210
  • [39] Cutting edge: Role of toll-like receptor 9 in CpG DNA-induced activation of human cells
    Takeshita, F
    Leifer, CA
    Gursel, I
    Ishii, KJ
    Takeshita, S
    Gursel, M
    Klinman, DM
    JOURNAL OF IMMUNOLOGY, 2001, 167 (07): : 3555 - 3558
  • [40] Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA
    Ramirez-Ortiz, Zaida G.
    Specht, Charles A.
    Wang, Jennifer P.
    Lee, Chrono K.
    Bartholomeu, Daniella C.
    Gazzinelli, Ricardo T.
    Levitz, Stuart A.
    INFECTION AND IMMUNITY, 2008, 76 (05) : 2123 - 2129
12345