Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation

被引:20
|
作者
Liu, Shan-shan [1 ,2 ]
Qi, Jie [1 ]
Teng, Zu-dong [3 ]
Tian, Fu-tao [3 ]
Lv, Xiao-xi [2 ]
Li, Ke [4 ]
Song, Ya-jie [1 ]
Xie, Wei-dong [2 ]
Hu, Zhuo-wei [2 ]
Li, Xia [1 ]
机构
[1] Shandong Univ, Dept Pharm, Marine Coll, Weihai 264209, Peoples R China
[2] Chinese Acad Med Sci & Peking Union Med Coll, Mol Immunol & Pharmacol Grp, State Key Lab Bioact Subst & Funct Nat Med, Inst Mat Med, Beijing 100050, Peoples R China
[3] Changle Peoples Hosp, Dept Pathol, Weifang 262499, Peoples R China
[4] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Biotechnol, Beijing 100050, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1038/s41392-020-00255-y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Angiotensin-(1-7) attenuates triple-negative breast cancer growth and progression through regulation of protein phosphatases
    Gallagher, Patricia E.
    Arter, Alison L.
    Soto-Pantoja, David R.
    Tallant, E. Ann
    CANCER RESEARCH, 2013, 73
  • [22] TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERa expression in triple-negative breast cancer
    Gao, Shang
    Sun, Ping
    Wang, Zekun
    Jin, Yecheng
    Sun, Wenjie
    Li, Xi
    Duan, Ruonan
    Li, Jiangxia
    Liu, Qiji
    GENES & DISEASES, 2025, 12 (02)
  • [23] The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
    Howley, Breege, V
    Mohanty, Bidyut
    Dalton, Annamarie
    Grelet, Simon
    Karam, Joseph
    Dincman, Toros
    Howe, Philip H.
    ONCOGENE, 2022, 41 (12) : 1679 - 1690
  • [24] The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
    Breege V. Howley
    Bidyut Mohanty
    Annamarie Dalton
    Simon Grelet
    Joseph Karam
    Toros Dincman
    Philip H. Howe
    Oncogene, 2022, 41 : 1679 - 1690
  • [25] Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells
    Zhao, Ke-Wen
    Sikriwal, Deepa
    Dong, Xueyuan
    Guo, Peng
    Sun, Xiaodong
    Dong, Jin-Tang
    BIOCHEMICAL JOURNAL, 2011, 437 : 323 - 333
  • [26] Prolactin and androgen R1881 induce pro-survival carboxypeptidase-D and EDD E3 ligase in triple-negative and HER2+breast cancer
    MacDonald, Tyler M.
    Thomas, Lynn N.
    Gupta, Aurinjoy
    Barnes, Penelope J.
    Too, Catherine K. L.
    AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 10 (05): : 1321 - 1343
  • [27] Ganoderic acid D attenuates gemcitabine resistance of triple-negative breast cancer cells by inhibiting glycolysis via HIF-1 α destabilization
    Luo, Binbin
    Song, Linyi
    Chen, Limiao
    Cai, Yue
    Zhang, Mingwei
    Wang, Shenyi
    PHYTOMEDICINE, 2024, 129
  • [28] BBOX1 promotes triple-negative breast cancer progression by controlling IP3R3 stability
    Liao, Chengheng
    Zhang, Qing
    MOLECULAR & CELLULAR ONCOLOGY, 2020, 7 (06)
  • [29] WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated Degradation in Breast Cancer Cells
    Yeung, Benjamin
    Ho, King-Ching
    Yang, Xiaolong
    PLOS ONE, 2013, 8 (04):
  • [30] Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1
    Wei, Chunli
    Khan, Md. Asaduzzaman
    Du, Jiaman
    Cheng, Jingliang
    Tania, Mousumi
    Leung, Elaine Lai-Han
    Fu, Junjiang
    FRONTIERS IN ONCOLOGY, 2022, 12