trans,trans-2,4-decadienal: Cytotoxicity and effect on glutathione level in human erythroleukemia (HEL) cells

被引：50
|
作者：
Nappez, C [1 ]
Battu, S [1 ]
Beneytout, JL [1 ]
机构：
[1] FAC MED & PHARM,CNRS,URA 1485,F-87025 LIMOGES,FRANCE
来源：
CANCER LETTERS | 1996年 / 99卷 / 01期
关键词：
HEL cells; hydroxyalkenals; trans,trans-2,4-decadienal; glutathione;
D O I：
10.1016/0304-3835(95)04045-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The effects of trans,trans-2,4-decadienal (DDE), an isomer of a lipid peroxidation product were investigated on the human erythroleukemia cell line (HEL TIB 180). DDE strongly inhibits cell growth and affects cell viability without any differentiating effects. DDE treatment of HEL cells leads to a marked variation of the cellular glutathione level (GSH) and is involved in the beginning of DNA fragmentation.
引用
收藏
页码：115 / 119
页数：5
相关论文
共 50 条
  • [41] Tributyrin plus all-trans-retinoic acid efficiently induces fetal hemoglobin expression in human erythroleukemia cells
    Witt, O
    Schmejkal, S
    Pekrun, A
    AMERICAN JOURNAL OF HEMATOLOGY, 2000, 64 (04) : 319 - 321
  • [42] Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells
    Rajabian, Fatemeh
    Mehri, Soghra
    Razavi, BiBi Marjan
    Rad, Abolfazl Khajavi
    Rahbardar, Mahboobeh Ghasemzadeh
    Hosseinzadeh, Hossein
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2023, 26 (02) : 148 - 156
  • [43] Effect of trans fatty acids on calcium influx into human arterial endothelial cells
    Kummerow, FA
    Zhou, Q
    Mahfouz, MM
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1999, 70 (05): : 832 - 838
  • [44] Combined dandelion extract and all-trans retinoic acid induces cytotoxicity in human breast cancer cells
    Hamed Rezaie
    Reza Alipanah-Moghadam
    Farhad Jeddi
    Cain C. T. Clark
    Vahideh Aghamohammadi
    Ali Nemati
    Scientific Reports, 13
  • [45] Combined dandelion extract and all-trans retinoic acid induces cytotoxicity in human breast cancer cells
    Rezaie, Hamed
    Alipanah-Moghadam, Reza
    Jeddi, Farhad
    Clark, Cain C. T.
    Aghamohammadi, Vahideh
    Nemati, Ali
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [46] Potent inhibitory effect of trans9, trans 11 isomer of conjugated linoleic acid on the growth of human colon cancer cells
    Beppu, Fumiaki
    Hosokawa, Masashi
    Tanaka, Leo
    Kohno, Hiroyuki
    Tanaka, Takuji
    Miyashita, Kazuo
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2006, 17 (12): : 830 - 836
  • [47] Cytotoxic effect of trans-cinnamaldehyde on human leukemia K562 cells
    Jia-hua Zhang
    Li-qiong Liu
    Yan-li He
    Wei-jia Kong
    Shi-ang Huang
    Acta Pharmacologica Sinica, 2010, 31 : 861 - 866
  • [48] Antioxidant Effect of Trans-Resveratrol in Cultured Human Retinal Pigment Epithelial Cells
    Pintea, Adela
    Rugina, Dumitrita
    Pop, Raluca
    Bunea, Andrea
    Socaciu, Carmen
    Diehl, Horst A.
    JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2011, 27 (04) : 315 - 321
  • [49] Cytotoxic effect of trans-cinnamaldehyde on human leukemia K562 cells
    Zhang, Jia-hua
    Liu, Li-qiong
    He, Yan-li
    Kong, Wei-jia
    Huang, Shi-ang
    ACTA PHARMACOLOGICA SINICA, 2010, 31 (07) : 861 - 866
  • [50] Comparison of A2E Cytotoxicity and Phototoxicity with all-trans-Retinal in Human Retinal Pigment Epithelial Cells†
    Wielgus, Albert R.
    Chignell, Colin F.
    Ceger, Patricia
    Roberts, Joan E.
    PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2010, 86 (04) : 781 - 791
12345