Highly enantioselective hydrogenation of α-keto esters catalyzed by Ru-tunephos complexes

被引：30
|
作者：
Wang, Chun-Jiang [1 ]
Sun, Xianfeng [1 ]
Zhang, Xumu [1 ]
机构：
[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA
来源：
SYNLETT | 2006年 / 08期
关键词：
asymmetric catalysis; enantioselectivity; ruthenium; hydrogenation; alpha-keto esters;
D O I：
10.1055/s-2006-932461
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Various enantiomerically pure alpha-hydroxy esters were synthesized by asymmetric hydrogenation of alpha-keto esters catalyzed by Ru-C-n-Tunephos complex. Up to 97.1% ee has been achieved for both alpha-aryl and alpha-alkyl substituted alpha-keto esters.
引用
收藏
页码：1169 / 1172
页数：4
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