Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes

被引：42
|
作者：
Zhao, Zi-Wen [1 ]
Lin, Chao-Gui [1 ]
Wu, Ling-Zhen [1 ]
Luo, Yu-Kun [1 ]
Fan, Lin [1 ]
Dong, Xian-feng [1 ]
Zheng, Hong [1 ]
机构：
[1] Fujian Med Univ, Fujian Inst Coronary Artery Dis, Union Hosp, Dept Cardiol, Fuzhou 350001, Peoples R China
来源：
BIOMARKERS | 2013年 / 18卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Biomarker; coronary artery disease; diabetes; fetuin-A; MYOCARDIAL-INFARCTION; METABOLIC SYNDROME; CARDIOVASCULAR-DISEASE; RANCHO BERNARDO; RISK; RESISTANCE; MORTALITY; LIVER; HEART;
D O I：
10.3109/1354750X.2012.762806
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Objective: To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM). Methods: A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG). Results: Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients. Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.
引用
收藏
页码：160 / 164
页数：5
相关论文
共 50 条
  • [21] Serum fetuin levels are associated with peripheral arterial disease in patients with type 2 diabetes mellitus
    Eleftheriadou, I.
    Grigoropoulou, P.
    Mourouzis, I.
    Liaskos, C.
    Kokkinos, A.
    Perrea, D.
    Makrilakis, K.
    Katsilambros, N.
    Tentolouris, N.
    DIABETOLOGIA, 2014, 57 : S523 - S523
  • [22] Effects of pioglitazone on serum fetuin-A levels in type 2 diabetic patients
    Mori, Katsuhito
    Emoto, Masanori
    Araki, Takahiro
    Lee, Eiko
    Yokoyama, Hisayo
    Teramura, Megumi
    Motoyama, Koka
    Koyama, Hidenori
    Shoji, Tetsuo
    Nishizawa, Yoshiki
    DIABETES, 2007, 56 : A162 - A162
  • [23] Serum Visfatin, Fetuin-A, and Pentraxin 3 Levels in Patients With Psoriasis and Their Relation to Disease Severity
    Okan, Gokhan
    Baki, Adile Merve
    Yorulmaz, Eda
    Dogru-Abbasoglu, Semra
    Vural, Pervin
    JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2016, 30 (04) : 284 - 289
  • [24] The prognostic role of Fetuin-A serum levels in patients with Coronary Artery Disease. Corellation with myocardium scintigraphy.
    Zissimopoulos, A.
    Psomiadou, A.
    Baloka, L.
    Karathanos, E.
    Thomaidou, A.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 : S537 - S537
  • [25] Plasma fetuin-A levels and the risk of type 2 diabetes
    Stefan, Norbert
    Fritsche, Andreas
    Weikert, Cornelia
    Boeing, Heiner
    Joost, Hans-Georg
    Haring, Hans-Ulrich
    Schulze, Matthias B.
    DIABETES, 2008, 57 (10) : 2762 - 2767
  • [26] Relationship between disease severity and fetuin-A levels in patients with psoriasis
    Shehata, Wafaa Ahmed
    Basha, Mohamed Ahmed
    Gayed, Iman Masoud
    Elhagary, Shaimaa Basyouny
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2020, 86 (05): : 586 - +
  • [27] Associations of Fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy
    Roos, Marcel
    Oikonomou, Dimitrios
    von Eynatten, Maximilian
    Luppa, Peter B.
    Heemann, Uwe
    Lutz, Jens
    Baumann, Marcus
    Nawroth, Peter P.
    Bierhaus, Angelika
    Humpert, Per M.
    CARDIOVASCULAR DIABETOLOGY, 2010, 9
  • [28] Associations of Fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy
    Marcel Roos
    Dimitrios Oikonomou
    Maximilian von Eynatten
    Peter B Luppa
    Uwe Heemann
    Jens Lutz
    Marcus Baumann
    Peter P Nawroth
    Angelika Bierhaus
    Per M Humpert
    Cardiovascular Diabetology, 9
  • [29] Increased serum levels of fetuin B in patients with coronary artery disease
    Zhu, Kefu
    Wang, Yuming
    Shu, Pengqin
    Zhou, Qinyi
    Zhu, Jinzhou
    Zhou, Wenjing
    Du, Changqing
    Xu, Chenkai
    Liu, Xiaowei
    Tang, Lijiang
    ENDOCRINE, 2017, 58 (01) : 97 - 105
  • [30] Increased serum levels of fetuin B in patients with coronary artery disease
    Kefu Zhu
    Yuming Wang
    Pengqin Shu
    Qinyi Zhou
    Jinzhou Zhu
    Wenjing Zhou
    Changqing Du
    Chenkai Xu
    Xiaowei Liu
    Lijiang Tang
    Endocrine, 2017, 58 : 97 - 105
12345