Hybrid Alginate-Based Cryogels for Life Science Applications

被引：16
|
作者：
Barros, Alexandre [1 ,2 ]
Quraishi, Sakeena [3 ]
Martins, Marta [1 ,2 ]
Gurikov, Pavel [3 ]
Subrahmanyam, Raman [3 ]
Smirnova, Irina [3 ]
Duarte, Ana Rita C. [1 ,2 ]
Reis, Rui L. [1 ,2 ]
机构：
[1] Univ Minho, Res Grp Biomat Biodegradables & Biomimet 3Bs, European Inst Excellence Tissue Engn & Regenerat, AvePk, P-4805017 Barco, Guimaraes, Portugal
[2] Univ Minho, ICVS PT Govt Associate Lab 3Bs, Life & Hlth Sci Res Inst ICVS, Campus Gualtar, P-4710057 Braga, Portugal
[3] Hamburg Univ Technol, Inst Thermal Separat Proc, Eissendorfer Str 38, D-21073 Hamburg, Germany
来源：
CHEMIE INGENIEUR TECHNIK | 2016年 / 88卷 / 11期
关键词：
Alginate; Cryogel; Freeze-drying; CARBON-DIOXIDE; BIOMEDICAL APPLICATIONS; REGENERATIVE MEDICINE; HYDROGELS; FABRICATION; SCAFFOLDS; BEHAVIOR; BIOMATERIALS; DEGRADATION; AEROGELS;
D O I：
10.1002/cite.201600096
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) applications. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two-step process. Textural properties of the cryogels were analyzed by SEM and micro-computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid-alginate cryogels did not present cytotoxicity and have the potential to be used in TERM.
引用
收藏
页码：1770 / 1778
页数：9
相关论文
共 50 条
  • [21] Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications
    Kavand, Alireza
    Noverraz, Francois
    Gerber-Lemaire, Sandrine
    PHARMACEUTICS, 2024, 16 (04)
  • [22] Development of alginate-based hydrogels: Crosslinking strategies and biomedical applications
    Tan, Junyan
    Luo, Yuning
    Guo, Yuqiong
    Zhou, Yue
    Liao, Xinying
    Li, Dingxilei
    Lai, Xinyi
    Liu, Yang
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 239
  • [23] Alginate-based active and intelligent packaging: Preparation, properties and applications
    Li, Hang
    Wang, Zongji
    Zhu, Fan
    Li, Guantian
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 279
  • [24] Characterization of an alginate-based drug delivery system for neurological applications
    Ciofani, Gianni
    Raffa, Vittoria
    Pizzorusso, Tommaso
    Menciassi, Arianna
    Dario, Paolo
    MEDICAL ENGINEERING & PHYSICS, 2008, 30 (07) : 848 - 855
  • [25] INNOVATIVE ALGINATE-BASED HYBRID COMPOSITE BEADS FOR HEAVY METALS REMOVAL
    Miron, Andreea
    Sarbu, Andrei
    Sandu, Teodor
    Gavrila, Ana-Mihaela
    Baroi, Anda Maria
    Chiriac, Anita-Laura
    Iordache, Tanta-Verona
    Iovu, Horia
    UNIVERSITY POLITEHNICA OF BUCHAREST SCIENTIFIC BULLETIN SERIES B-CHEMISTRY AND MATERIALS SCIENCE, 2024, 86 (01): : 3 - 18
  • [26] INNOVATIVE ALGINATE-BASED HYBRID COMPOSITE BEADS FOR HEAVY METALS REMOVAL
    Miron, Andreea
    Sarbu, Andrei
    Sandu, Teodor
    Gavrila, Ana-Mihaela
    Baroi, Anda Maria
    Chiriac, Anita-Laura
    Iordache, Tanta-Verona
    Iovu, Horia
    UPB Scientific Bulletin, Series B: Chemistry and Materials Science, 2024, 86 (01): : 3 - 18
  • [27] Alginate-based Composite Microspheres: Preparations and Applications for Bone Tissue Engineering
    Jayachandran, Venkatesan
    Murugan, Sesha Subramanian
    Dalavi, Pandurang Appana
    Vishalakshi, Yashaswini Devi Gurushanthappa
    Seong, Gi Hun
    CURRENT PHARMACEUTICAL DESIGN, 2022, 28 (13) : 1067 - 1081
  • [28] Recent advancements in alginate-based films for active food packaging applications
    Metha, Chaitanya
    Pawar, Shrutee
    Suvarna, Vasanti
    SUSTAINABLE FOOD TECHNOLOGY, 2024, 2 (05): : 1246 - 1265
  • [29] A review of sodium alginate-based hydrogels: Structure, mechanisms, applications, and perspectives
    Wang, Hong
    Yang, Liang
    Yang, Yanning
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 292
  • [30] Alginate-Based Emulsions and Hydrogels for Extending the Shelf Life of Banana Fruit
    Iacovino, Silvio
    Cofelice, Martina
    Sorrentino, Elena
    Cuomo, Francesca
    Messia, Maria Cristina
    Lopez, Francesco
    GELS, 2024, 10 (04)
12345