Regioselective synthesis and stereochemical structure of 1,2,8,9,13-pentaazadispiro[4.1.4.3]tetradeca-2,9-dien-6-ones

被引：0

作者：

Girgis, AS ^{[1
]}

机构：

[1] Natl Res Ctr, Dept Pesticide Chem, Cairo 12622, Egypt

来源：

JOURNAL OF CHEMICAL RESEARCH-S | 2006年 / 02期

关键词：

1,2,8,9,13-pentaazadispiro[4.1.4.3]tetradeca-2,9-dien-6-ones; 3,5-bis(arylmethylene)-4-piperidinones; nitrilimines; 1,3-dipolar cycloaddition reactions;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile regioselective synthetic approach towards 1,3,4,8,10,11-hexaaryl-13-methyl-1,2,8,9,13-pentaazadispiro [4.1.4.3]tetradeca-2,9-dien-6-ones 3a-g was achieved through the reaction of 3,5-bis(arylmethylene)-1-methyl-4-piperidinones 1a-f with nitrilimines (generated in situ by triethylamine dehydrohalogenation of the corresponding hydrazonoyl chlorides 2a,b). The stereochemical configuration of the isolated products was established to be 4S, 5R, 7R, 11S based on a single crystal X-ray diffraction study of 3b.

引用

页码：127 / 129

页数：3

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