Body Mass Index as a Predictor of All-Cause Mortality in Nursing Home Residents During a 5-Year Follow-up

被引:39
|
作者
Veronese, Nicola [1 ]
De Rui, Marina [1 ]
Toffanello, Elena Debora [1 ]
De Ronch, Irene [1 ]
Perissinotto, Egle [2 ]
Bolzetta, Francesco [1 ]
D'Avanzo, Barbara [1 ]
Cardin, Fabrizio [3 ]
Coin, Alessandra [1 ]
Manzato, Enzo [1 ]
Sergi, Giuseppe [1 ]
机构
[1] Univ Padua, Dept Med DIMED, Div Geriatr, Padua, Italy
[2] Univ Padua, Dept Cardiac Thorac & Vasc Sci, Padua, Italy
[3] Univ Padua, Dept Geriatr, Div Geriatr Surg, I-35100 Padua, Italy
关键词
Body mass index; nursing home; mortality; elderly; nutrition; COMPREHENSIVE GERIATRIC ASSESSMENT; MULTIDIMENSIONAL PROGNOSTIC INDEX; MINI-NUTRITIONAL ASSESSMENT; TERM MORTALITY; VALIDATION; RISK; POPULATION; SURVIVAL; ALBUMIN; 4-YEAR;
D O I
10.1016/j.jamda.2012.09.014
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: Body mass index (BMI) is considered a short-term mortality predictor, but a consensus has not been reached on its role and that of other nutritional parameters in predicting long-term mortality in nursing home residents. Objectives: To correlate BMI, Mini Nutritional Assessment scores, and serum albumin levels with the 5-year mortality rate in institutionalized elderly subjects. Methods: A total of 181 nursing home residents aged >= 70 years were included in a 5-year longitudinal study. Data were collected on all participants' nutritional, health, cognitive, and functional status by means of a comprehensive geriatric assessment. Data on the participants' vital status were obtained 5 years after beginning the study, and a survival analysis was conducted using Kaplan-Meier curves and multivariate Cox proportional hazards models. Results: The 5-year mortality rate was 63%. The deceased subjects (n = 115) had a lower BMI (24.7 +/- 4.6 vs 26.6 +/- 5.0 kg/m(2); P=.03) and Mini Nutritional Assessment score (18.6 +/- 3.7 vs 20.1 +/- 3.6; P=.02) than those still alive. Serum albumin levels did not differ between the two groups. Among the three indicators of nutritional status considered in this study, only BMI >= 30 kg/m(2) was significantly associated with a lower mortality risk at 5 years (hazard ratio = 0.432; 95% CI 0.20-0.70; P=.04), the risk for death being greater the lower the BMI class (log-rank test: P < .001). Conclusions: Our findings suggest that BMI is the best of the three parameters considered as a nutritional predictor of nursing home residents' mortality in the longer term, and indicate that a lower mortality risk coincides with a higher BMI. Copyright (C) 2013 - American Medical Directors Association, Inc.
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页码:53 / 57
页数:5
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