The synthesis of novel N-heterocyclic -diphenylphosphinoglycines

被引:6
|
作者
Fomina, Olga S. [1 ,2 ]
Heinicke, Joachim W. [2 ]
Sinyashin, Oleg G. [1 ]
Yakhvarov, Dmitry G. [1 ]
机构
[1] Russian Acad Sci, Kazan Sci Ctr, AE Arbuzov Inst Organ & Phys Chem, Arbuzov Str 8, Kazan 420088, Russia
[2] Ernst Moritz Arndt Univ Greifswald, Inst Biochem, Greifswald, Germany
关键词
Amino acids; glycines; glycolates; phosphino amino acids; three-component reaction; AMINO-ACIDS;
D O I
10.1080/10426507.2016.1212046
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The one-pot reaction of glyoxylic acid hydrate with diphenyl phosphine and a heretocyclic primary amine in methanol results in formation of first examples of N-hererocyclic -diphenylphosphinoglycines bearing imidazo[4,5-d]-pyrimidine-6-yl, 4,6-dimethylpyrimidin-2-yl, pyridine-2-yl and pyridine-3-yl substituents. [GRAPHICS] .
引用
收藏
页码:1478 / 1479
页数:2
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