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The synthesis of novel N-heterocyclic -diphenylphosphinoglycines
被引:6
|作者:
Fomina, Olga S.
[1
,2
]
Heinicke, Joachim W.
[2
]
Sinyashin, Oleg G.
[1
]
Yakhvarov, Dmitry G.
[1
]
机构:
[1] Russian Acad Sci, Kazan Sci Ctr, AE Arbuzov Inst Organ & Phys Chem, Arbuzov Str 8, Kazan 420088, Russia
[2] Ernst Moritz Arndt Univ Greifswald, Inst Biochem, Greifswald, Germany
关键词:
Amino acids;
glycines;
glycolates;
phosphino amino acids;
three-component reaction;
AMINO-ACIDS;
D O I:
10.1080/10426507.2016.1212046
中图分类号:
O61 [无机化学];
学科分类号:
070301 ;
081704 ;
摘要:
The one-pot reaction of glyoxylic acid hydrate with diphenyl phosphine and a heretocyclic primary amine in methanol results in formation of first examples of N-hererocyclic -diphenylphosphinoglycines bearing imidazo[4,5-d]-pyrimidine-6-yl, 4,6-dimethylpyrimidin-2-yl, pyridine-2-yl and pyridine-3-yl substituents. [GRAPHICS] .
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页码:1478 / 1479
页数:2
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