Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides

被引:11
|
作者
Zhang, Dongxin [1 ]
Man, Jingjing [1 ]
Chen, Yan [1 ]
Yin, Lei [1 ]
Zhong, Junchao [1 ]
Zhang, Qian-Feng [1 ]
机构
[1] Anhui Univ Technol, Inst Mol Engn & Appl Chem, 59 Hudong Rd, Maanshan 243002, Peoples R China
关键词
BIOACTIVE BENZOFURAN; DERIVATIVES; EFFICIENT; ANNULATION; ARYLATION; ACCESS;
D O I
10.1039/c9ra02144b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans were able to be efficiently synthesized all from simple and inexpensive starting materials in two steps.
引用
收藏
页码:12567 / 12571
页数:5
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