Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides

被引：11

作者：

Zhang, Dongxin ^{[1
]}

Man, Jingjing ^{[1
]}

Chen, Yan ^{[1
]}

Yin, Lei ^{[1
]}

Zhong, Junchao ^{[1
]}

Zhang, Qian-Feng ^{[1
]}

机构：

[1] Anhui Univ Technol, Inst Mol Engn & Appl Chem, 59 Hudong Rd, Maanshan 243002, Peoples R China

来源：

RSC ADVANCES | 2019年 / 9卷 / 22期

关键词：

BIOACTIVE BENZOFURAN; DERIVATIVES; EFFICIENT; ANNULATION; ARYLATION; ACCESS;

D O I：

10.1039/c9ra02144b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans were able to be efficiently synthesized all from simple and inexpensive starting materials in two steps.

引用

页码：12567 / 12571

页数：5

共 50 条

[1] Efficient synthesis of functionalized furans and benzofurans based on a '[3+2] cyclization/oxidation' strategy
Bellur, E
Freifeld, I
Langer, P
TETRAHEDRON LETTERS, 2005, 46 (13) : 2185 - 2187
[2] Step Economy in the Stereoselective Synthesis of Functionalized Oxindoles via Organocatalytic Domino/One-pot Reactions
Bortolami, Martina
Leonelli, Francesca
Feroci, Marta
Vetica, Fabrizio
CURRENT ORGANIC CHEMISTRY, 2021, 25 (11) : 1321 - 1344
[3] One-pot synthesis of novel functionalized benzodiazepines via three-component or domino reactions
Sun, Yue-Wei
Wang, Lan-Zhi
NEW JOURNAL OF CHEMISTRY, 2018, 42 (24) : 20032 - 20040
[4] One-Pot Synthesis of Benzofurans via Cu-Catalyzed Tandem Sonogashira Coupling-Cyclization Reactions
Thomas, Anns Maria
Asha, Sujatha
Menon, Rajasree
Anilkumar, Gopinathan
CHEMISTRYSELECT, 2019, 4 (19): : 5544 - 5547
[5] DABCO-catalyzed multi-component domino reactions for the one-pot efficient synthesis of diverse and densely functionalized benzofurans in water
Golchin, Sajedeh
Mosslemin, Mohammad Hossein
Yazdani-Elah-Abadi, Afshin
Shams, Nasim
RESEARCH ON CHEMICAL INTERMEDIATES, 2017, 43 (03) : 1735 - 1749
[6] DABCO-catalyzed multi-component domino reactions for the one-pot efficient synthesis of diverse and densely functionalized benzofurans in water
Sajedeh Golchin
Mohammad Hossein Mosslemin
Afshin Yazdani-Elah-Abadi
Nasim Shams
Research on Chemical Intermediates, 2017, 43 : 1735 - 1749
[7] Diastereoselective Synthesis of Arylidene Bis(3-arylaminoacrylates) via One-pot Domino Reactions
Liu, Zhenming
Zhang, Lili
Sun, Jing
Yan, Chaoguo
CHINESE JOURNAL OF CHEMISTRY, 2013, 31 (04) : 479 - 484
[8] Sequential one-pot approach for the synthesis of functionalized phthalans via Heck-reduction-cyclization (HRC) reactions
Krishna, Jonnada
Niharika, Pedireddi
Satyanarayana, Gedu
RSC ADVANCES, 2015, 5 (34) : 26749 - 26761
[9] Synthesis of Isoxazoles via One-Pot Oxidation/Cyclization Sequence from Propargylamines
Duan, Mengyan
Hou, Guodong
Zhao, Yabiao
Zhu, Congjun
Song, Chuanjun
JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (16): : 11222 - 11225
[10] Domino Oxidative Cyclization of 2-Aminoacetophenones for the One-Pot Synthesis of Tryptanthrin Derivatives
Reddy, B. V. Subba
Reddy, D. Maheswara
Reddy, G. Niranjan
Reddy, M. Ramana
Reddy, V. Krishna
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 2015 (36) : 8018 - 8022

← 1 2 3 4 5 →