One-pot mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines

被引：84

作者：

Strukil, Vjekoslav ^{[1
]}

Bartolec, Boris ^{[1
]}

Portada, Tomislav ^{[1
]}

Dilovic, Ivica ^{[2
]}

Halasz, Ivan ^{[3
]}

Margetic, Davor ^{[1
]}

机构：

[1] Rudjer Boskovic Inst, Div Organ Chem & Biochem, HR-10002 Zagreb, Croatia

[2] Univ Zagreb, Fac Sci, Dept Chem, Zagreb 41000, Croatia

[3] Rudjer Boskovic Inst, Div Chem Mat, HR-10002 Zagreb, Croatia

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 99期

关键词：

ASYMMETRIC ALDOL REACTION; (S)-PROLINE-CONTAINING DIPEPTIDES; GREEN SYNTHESIS; BOND FORMATION; SOLID-STATE; ORGANOCATALYSTS; DIFFRACTION;

D O I：

10.1039/c2cc36613d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.

引用

页码：12100 / 12102

页数：3

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