Processed meat consumption and risk of cancer: a multisite case-control study in Uruguay

被引：35
|
作者：
De Stefani, E. [1 ]
Boffetta, P. [2 ]
Ronco, A. L. [3 ]
Deneo-Pellegrini, H. [1 ]
Correa, P. [4 ]
Acosta, G. [1 ]
Mendilaharsu, M. [1 ]
Luaces, M. E. [1 ]
Silva, C. [1 ]
机构：
[1] Univ Republica, Sch Med, Dept Pathol, Epidemiol Grp, Montevideo, Uruguay
[2] Mt Sinai Sch Med, Tisch Canc Inst, New York, NY USA
[3] IUACLAEH Univ Maldonado, Dept Epidemiol, Maldonado, Uruguay
[4] Vanderbilt Univ, Med Ctr, Div Gastroenterol Hepatol & Nutr, Nashville, TN USA
来源：
BRITISH JOURNAL OF CANCER | 2012年 / 107卷 / 09期
关键词：
oesophageal cancer; gastric cancer; colorectal cancer; lung cancer; breast cancer; prostate cancer; BREAST-CANCER; PROSPECTIVE COHORT; STOMACH-CANCER; GASTRIC-CANCER; SALT; RED;
D O I：
10.1038/bjc.2012.433
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
BACKGROUND: The role of processed meat in the aetiology of several cancers was explored in detail. METHODS: In the time period 1996-2004, a multisite case-control study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity, pharynx, oesophagus, stomach, colon, rectum, larynx, lung, female breast, prostate, urinary bladder, and kidney (renal cell carcinoma only). RESULTS: The highest odds ratios (ORs) were positively associated with cancers of the colon, rectum, stomach, oesophagus, and lung. With the exception of renal cell carcinoma, the remaining cancer sites were significantly associated with elevated risks for processed meat consumption. Furthermore, mortadella, salami, hot dog, ham, and salted meat were strongly associated with risk of several cancer sites. CONCLUSION: It could be concluded that processed meat intake could be a powerful multiorgan carcinogen. British Journal of Cancer (2012) 107, 1584-1588. doi:10.1038/bjc.2012.433 www.bjcancer.com Published online 25 September 2012 (C) 2012 Cancer Research UK
引用
收藏
页码：1584 / 1588
页数：5
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