A cellular sense of touch

被引：2
|
作者：
He, Li [1 ]
Montell, Denise [2 ,3 ]
机构：
[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA
[2] Johns Hopkins Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA
[3] Johns Hopkins Sch Med, Ctr Cell Dynam, Baltimore, MD 21205 USA
来源：
NATURE CELL BIOLOGY | 2012年 / 14卷 / 09期
关键词：
INTEGRIN ACTIVATION; MECHANICAL TENSION; FOCAL ADHESIONS; MECHANOTRANSDUCTION; DYNAMICS; FORCES; MATRIX;
D O I：
10.1038/ncb2572
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
How cells sense and respond to physical forces is an area of intense investigation, which poses significant challenges for in vitro experiments and even greater obstacles for in vivo studies. Analyses of integrin complex dynamics in Drosophila melanogaster now provide evidence that altering mechanical force modulates the stability of integrin adhesion in vivo.
引用
收藏
页码：902 / 903
页数：2
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