Predictive value of fasting blood glucose for serious coronary atherosclerosis in non-diabetic patients

被引：11
|
作者：
Zhao, Tong [1 ]
Gong, Hui-Ping [1 ]
Dong, Zhao-Qiang [1 ]
Du, Yi-Meng [1 ]
Lu, Qing-Hua [1 ]
Chen, Hui-Qiang [1 ]
机构：
[1] Shandong Univ, Hosp 2, Dept Cardiol, Jinan, Shandong, Peoples R China
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2019年 / 47卷 / 01期
关键词：
Fasting blood glucose; coronary artery disease; Gensini score; diabetes mellitus; hyperglycemia; prediction; ARTERY-DISEASE; SYNTAX SCORE; CARDIOVASCULAR-DISEASE; HEMOGLOBIN A1C; SEVERITY; RISK; PREVALENCE;
D O I：
10.1177/0300060518798252
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective To determine if high fasting blood glucose (FBG) level is an independent predictor of serious coronary lesions in patients with coronary artery disease (CAD). Methods We enrolled 64 patients who had symptoms of chest discomfort and who underwent coronary angiography. FBG was determined from blood samples and the extent of coronary artery lesions was analyzed according to Gensini score. We examined the relationships among diabetes, FBG, and coronary artery severity. Results Diabetes and FBG were significantly and positively related to Gensini score. Diabetes, but not FBG, was independently correlated with the occurrence of a Gensini score >41. However, FBG was significantly associated with Gensini score >41 in non-diabetic patients. Conclusion Hyperglycemia is an independent predictor of severe CAD in non-diabetic patients. Clinicians should be aware of this and should carry out appropriate early interventions.
引用
收藏
页码：152 / 158
页数：7
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