Application Status and Prospect of Carbon-Based Nanomaterials in Biomedical Field

被引:0
|
作者
Zhang Jinchao [1 ]
Yang Kangning [1 ]
Zhang Haisong [3 ]
Liang Xingjie [2 ]
机构
[1] Hebei Univ, Coll Chem & Environm Sci, Chem Biol Key Lab Hebei Prov, Baoding 071002, Peoples R China
[2] CAS Key Lab Biomed Effects Nanomat & Nanosafety, Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[3] Hebei Univ, Affiliated Hosp, Baoding 071000, Peoples R China
关键词
carbon-based nanomaterials; carbon nanotubes; fullerene; graphene; nanodiamond; NANO-GRAPHENE OXIDE; NEURAL STEM-CELLS; IN-VITRO; FULLERENE C-60; DIAMOND NANOPARTICLES; PULMONARY TOXICITY; HIGH-EFFICIENCY; DRUG-DELIVERY; NANOTUBES; DIFFERENTIATION;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanomaterials have become a new type of materials with a rapid development of nanotechnology. Nanomaterials have unique physical and chemical properties such as small size effect, large surface area, high reactivity, and quantum effects. These features make the nanoscience as one of the three pillars of the world science. Carbon-based nanomaterials are an important part of nanomaterials, they include carbon nanotubes, fullerene, graphene, nanodiamond and their derivatives. Due to their unique physical and chemical properties, carbon-based nanomaterials have broad applications in the biomedical field. In addition, with the industrialization of nanotechnology,, various forms of carbon-based nanomaterials have come into human life in different ways, and the biosafety is increasingly attracting attention of scientists around the world. This article reviews the potential applications of all four types of carbon-based nanomaterials in the biomedical field including tissue engineering, drug/gene carrier, biological imaging, cancer treatment, anti-HIV/anti-bacterial activity, and biological sensing. In addition, the biosafety issue is also reviewed. Finally, we discuss the need for future research. Specifically, we identify the most important research topics, which urgently need to be studied.
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页码:397 / 408
页数:12
相关论文
共 109 条
  • [61] Paramagnetic water-soluble metallofullerenes having the highest relaxivity for MRI contrast agents
    Mikawa, M
    Kato, H
    Okumura, M
    Narazaki, M
    Kanazawa, Y
    Miwa, N
    Shinohara, H
    [J]. BIOCONJUGATE CHEMISTRY, 2001, 12 (04) : 510 - 514
  • [62] Graphene-Based Single-Bacterium Resolution Biodevice and DNA Transistor: Interfacing Graphene Derivatives with Nanoscale and Microscale Biocomponents
    Mohanty, Nihar
    Berry, Vikas
    [J]. NANO LETTERS, 2008, 8 (12) : 4469 - 4476
  • [63] Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism
    Mroz, Pawel
    Pawlak, Anna
    Satti, Minahil
    Lee, Haeryeon
    Wharton, Tim
    Gali, Hariprasad
    Sarna, Tadeusz
    Hamblin, Michael R.
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2007, 43 (05) : 711 - 719
  • [64] Ou Z M, 2009, ACTA OPTICAL SINIC S, VS1, P181
  • [65] Functionalized carbon nanotubes for plasmid DNA gene delivery
    Pantarotto, D
    Singh, R
    McCarthy, D
    Erhardt, M
    Briand, JP
    Prato, M
    Kostarelos, K
    Bianco, A
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (39) : 5242 - 5246
  • [66] Buckysomes: Fullerene-based nanocarriers for hydrophobic molecule delivery
    Partha, Ranga
    Mitchell, Linsey R.
    Lyon, Jennifer L.
    Joshi, Pratixa P.
    Conyers, Jodie L.
    [J]. ACS NANO, 2008, 2 (09) : 1950 - 1958
  • [67] Synthesis and in vitro testing of a pyropheophorbide-a-fullerene hexakis adduct immunoconjugate for photodynamic therapy
    Rancan, Fiorenza
    Helmreich, Matthias
    Moelich, Andreas
    Ermilov, Eugeny A.
    Jux, Norbert
    Roeder, Beate
    Hirsch, Andreas
    Boehm, Fritz
    [J]. BIOCONJUGATE CHEMISTRY, 2007, 18 (04) : 1078 - 1086
  • [68] Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy
    Robinson, Joshua T.
    Tabakman, Scott M.
    Liang, Yongye
    Wang, Hailiang
    Casalongue, Hernan Sanchez
    Daniel Vinh
    Dai, Hongjie
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (17) : 6825 - 6831
  • [69] Rui M. M., 2010, P NATL ACAD SCI USA, V107, P5339
  • [70] Graphene Oxide: A Nonspecific Enhancer of Cellular Growth
    Ruiz, Oscar N.
    Fernando, K. A. Shirai
    Wang, Baojiang
    Brown, Nicholas A.
    Luo, Pengju George
    McNamara, Nicholas D.
    Vangsness, Marlin
    Sun, Ya-Ping
    Bunker, Christopher E.
    [J]. ACS NANO, 2011, 5 (10) : 8100 - 8107