Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

被引:0
|
作者
Chien, Wenwen [1 ]
Sun, Qiaoyang [1 ]
Lim, Su Lin [1 ]
Varela, Ana D. S. M. [1 ]
Sun, Haibo [2 ]
Gery, Sigai [2 ]
Koeffier, H. Phillip [1 ]
机构
[1] Natl U Singapore, Canc Sci Inst, Singapore, Singapore
[2] Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA
关键词
D O I
10.1158/1538-7445.AM2013-4042
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4042
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Triptolide induces apoptosis in pancreatic cancer cells via inhibition of heat shock protein 70 (HSP70)
    Phillips, P. A.
    Dudeja, V.
    Sharif, R.
    Dawra, R.
    Saluja, A.
    PANCREAS, 2006, 33 (04) : 491 - 491
  • [32] IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis
    Zhang, Liling
    Nosak, Courtney
    Sollazzo, Pietro
    Odisho, Tanya
    Volchuk, Allen
    BMC CELL BIOLOGY, 2014, 15
  • [33] IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis
    Liling Zhang
    Courtney Nosak
    Pietro Sollazzo
    Tanya Odisho
    Allen Volchuk
    BMC Cell Biology, 15
  • [34] Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response
    Liang, Guodong
    Fang, Xuedong
    Yang, Yubo
    Song, Yan
    BIOCHEMISTRY AND CELL BIOLOGY, 2018, 96 (03) : 332 - 341
  • [35] The unfolded protein response induces the resistance of hepatoma cells to NK cells' cytotoxicity
    Chen, Lihua
    Gong, Jiu Yu
    Liu, Rongrong
    Fang, Liang
    Zhuang, Ran
    Zhang, Yun
    Jin, Boquan
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [36] Eicosapentaenoic Acid Induces Apoptosis in Pancreatic Cancer Cells
    Chen, M. C.
    Takahashi, H.
    Park, J. L.
    Pham, H.
    Reber, H. A.
    Hines, O. J.
    Go, V. L. W.
    Eibl, G.
    PANCREAS, 2010, 39 (08) : 1314 - 1314
  • [37] Focused ultrasound induces apoptosis in pancreatic cancer cells
    Guo Qian
    Jiang Li-xin
    Hu Bing
    CHINESE MEDICAL JOURNAL, 2012, 125 (12) : 2089 - 2093
  • [38] Focused ultrasound induces apoptosis in pancreatic cancer cells
    GUO QianJIANG Lixin and HU Bing Department of Ultrasound in MedicineSixth Peoples Hospital Affiliated to Shanghai Jiao Tong UniversityShanghai China Shanghai Institute of Ultrasound in MedicineShanghai China
    中华医学杂志(英文版), 2012, (12) : 2089 - 2093
  • [39] A Potent Lead Induces Apoptosis in Pancreatic Cancer Cells
    Liu, Zuojia
    Li, Dan
    Zhao, Wenjing
    Zheng, Xiliang
    Wang, Jin
    Wang, Erkang
    PLOS ONE, 2012, 7 (06):
  • [40] Rhenium isonitrile complexes induce unfolded protein response-mediated apoptosis in cancer cells
    Marker, Sierra
    King, Arthur
    Swanda, Robert
    Wilson, Justin
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258