INAA method optimization using a 2k factorial design

In this work a 2(3) factorial design was carried out aiming the multivariate optimization of Instrumental Neutron Activation Analysis (INAA) for mass fraction determination of Co, Cr, Fe, Rb, Sc, Se and Zn in biological samples and Co, Cr, Fe, Sc and Zn in geological samples. The factors investigated in this study were sample decay time, sample distance to detector and sample measurement time. The optimal condition for each method was outlined according to the main effect and interactions results. It was observed that sample decay time is the most important factor for the INAA optimization in the different methods.