Treatment with Histone Deacetylase Inhibitors Creates 'BRCAness' and Sensitizes Human Triple Negative Breast Cancer Cells to PARP Inhibitors and Cisplatin

被引:6
|
作者
Bhalla, K. N. [1 ]
Rao, R. [1 ]
Sharma, P. [1 ]
Das Gupta, S. [1 ]
Chauhan, L. [1 ]
Stecklein, S. [1 ]
Fiskus, W. [1 ]
机构
[1] Univ Kansas, Ctr Canc, Kansas City, KS USA
关键词
D O I
10.1158/0008-5472.SABCS12-S3-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
S3-7
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Judy Garber on PARP inhibitors for triple-negative breast cancer
    Garber, Judy
    ONCOLOGY-NEW YORK, 2017, 31 (11): : 814 - +
  • [22] Unexpected selectivity of histone deacetylase inhibitors in live MDA-MD-231 triple-negative breast cancer cells
    Aboukhatwa, Shaimaa M.
    Hanigan, Thomas W.
    Neerasa, Jayaprakash
    Taha, Taha Y.
    Brown, Nathan D.
    El-Bastawissy, Eman E.
    Elkersh, Mohamed A.
    El-Moselhy, Tarek F.
    Frasor, Jonna
    Petukhov, Pavel A.
    CANCER RESEARCH, 2018, 78 (13)
  • [23] Synergistic induccion of apoptosis in human breast cancer cells by proteasome and histone deacetylase inhibitors
    Domingo-Domenech, Josep
    Tapia, Marian
    Gascon, Pere
    Albanell, Joan
    Bachs, Oriol
    Bosch, Marta
    CANCER RESEARCH, 2006, 66 (08)
  • [24] Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity
    Wu, Bocheng
    Fathi, Shaghayegh
    Mortley, Shanee
    Mohiuddin, Mahir
    Jang, Young C.
    Oyelere, Adegboyega K.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 28 (06)
  • [25] Molecular Signatures Associated with Treatment of Triple-Negative MDA-MB231 Breast Cancer Cells with Histone Deacetylase Inhibitors JAHA and SAHA
    Librizzi, Mariangela
    Caradonna, Fabio
    Cruciata, Ilenia
    Debski, Janusz
    Sansook, Supojjanee
    Dadlez, Michal
    Spencer, John
    Luparello, Claudio
    CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 30 (12) : 2187 - 2196
  • [26] New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer
    Han, Ye
    Yu, Xiaopeng
    Li, Shuqiang
    Tian, Ye
    Liu, Caigang
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [27] Histone-deacetylase inhibitors for the treatment of cancer
    Lindemann, RK
    Gabrielli, B
    Johnstone, RW
    CELL CYCLE, 2004, 3 (06) : 779 - 788
  • [28] Development of histone deacetylase inhibitors for cancer treatment
    Marchion, Douglas
    Muenster, Pamela
    EXPERT REVIEW OF ANTICANCER THERAPY, 2007, 7 (04) : 583 - 598
  • [29] Epigenetic reprogramming of epithelial-mesenchymal transition in triple-negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors
    Su, Yanrong
    Hopfinger, Nathan R.
    Pogash, Thomas J.
    Nguyen, Theresa D.
    Santucci-Pereira, Julia
    Russo, Jose
    CANCER RESEARCH, 2014, 74 (19)
  • [30] Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors
    Bamberg, Leonhard Valentin
    Heigwer, Florian
    Wandmacher, Anna Maxi
    Singh, Ambika
    Betge, Johannes
    Rindtorff, Niklas
    Werner, Johannes
    Josten, Julia
    Skabkina, Olga Valerievna
    Hinsenkamp, Isabel
    Erdmann, Gerrit
    Roecken, Christoph
    Ebert, Matthias P.
    Burgermeister, Elke
    Zhan, Tianzuo
    Boutros, Michael
    INTERNATIONAL JOURNAL OF CANCER, 2022, 151 (09) : 1586 - 1601