LANDSCAPE OF TARGETABLE BRAF ALTERATIONS AND RAF1 FUSIONS IN PEDIATRIC MALIGNANCY

被引:0
|
作者
Rankin, Andrew [1 ]
Johnson, Adrienne [1 ]
Rosenzweig, Mark [1 ]
Knipstein, Jeffrey [1 ]
Kannan, Geoffrey [1 ]
Britt, Nicholas [1 ]
Pavlick, Dean [1 ]
Vergilio, Jo-Anne [1 ]
Severson, Eric [1 ]
Erlich, Rachel [1 ]
Squillace, Rachel [1 ]
Stephens, Phil [1 ]
Miller, Vince [1 ]
Ross, Jeffrey [1 ]
Ramkissoon, Shakti [1 ]
Ali, Siraj [1 ]
机构
[1] Fdn Med Inc, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
801
引用
收藏
页数:2
相关论文
共 45 条
  • [31] Two cases of spindle cell tumors with S100 and CD34 co-expression showing novel RAF1 fusions
    Li-Hua Gong
    Wei-Feng Liu
    Xiao-Hui Niu
    Yi Ding
    Diagnostic Pathology, 17
  • [32] Small cell lung carcinoma harbors targetable alterations including MYCL1 fusions responding to aurora kinase inhibitor
    Ali, S.
    Kolla, B.
    Bailey, M.
    Schrock, A. B.
    Klempner, S. J.
    Frampton, G. M.
    Fabrizio, D. A.
    Ou, S-H. I.
    He, J.
    Suh, J.
    Ross, J. S.
    Stephens, P.
    Miller, V.
    Patel, M.
    ANNALS OF ONCOLOGY, 2016, 27
  • [33] A Novel Targetable RAF1-QKI Fusion in Adult Spinal Pleomorphic Xanthoastrocytoma without BRAF V600E Mutation
    Daoud, Elena
    Richardson, Timothy
    Mella, Divya
    Pan, Edward
    Schwarzbach, Anna
    White, Charles, III
    Hatanpaa, Kimmo
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2018, 77 (06): : 497 - 497
  • [34] An RNAi-based system for loss-of-function analysis: Identification of Raf1 but not BRAF as a crucial mediator of BCR-ABL-driven leukemogenesis
    Albers, C.
    Illert, A. L.
    Leischner, H.
    Miething, C.
    Peschel, C.
    Duyster, J.
    ONKOLOGIE, 2012, 35 : 170 - 170
  • [35] Acteoside (Verbascoside): A Prospective Therapeutic Alternative against Hepatocellular Carcinoma by Inhibiting the Expression of AXL, FGFR, BRAF, TIE2 and RAF1 Targets
    Kityania, Sibashish
    Nath, Rajat
    Nath, Deepa
    Patra, Jayanta Kumar
    Das Talukdar, Anupam
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023, 26 (10) : 1907 - 1919
  • [36] Transcription Defects in SF3B1K700E Induce Targetable Alterations in the Chromatin Landscape
    Boddu, Prajwal
    Gupta, Abhishek
    Roy, Rahul
    Herrero, Anne Olazabal
    Verma, Amit
    Neugebauer, Karla
    Pillai, Manoj
    BLOOD, 2023, 142
  • [37] Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    Boddu, Prajwal C.
    Gupta, Abhishek K.
    Roy, Rahul
    Avalos, Barbara De La Pena
    Olazabal-Herrero, Anne
    Neuenkirchen, Nils
    Zimmer, Joshua T.
    Chandhok, Namrata S.
    King, Darren
    Nannya, Yasuhito
    Ogawa, Seishi
    Lin, Haifan
    Simon, Matthew D.
    Dray, Eloise
    Kupfer, Gary M.
    Verma, Amit
    Neugebauer, Karla M.
    Pillai, Manoj M.
    MOLECULAR CELL, 2024, 84 (08) : 1475 - 1495.e18
  • [38] FUNCTIONAL CHARACTERIZATION AND EFFECTIVE TARGETING OF NRF1-BRAF AND ATG7-RAF1 FUSIONS IDENTIFIED IN ANAPLASTIC PLEOMORPHIC XANTHOASTROCYTOMA PATIENTS WITHOUT BRAF P.V600E MUTATION
    Sonawane, Poonam
    Diviney, Patrick
    Phillips, Joanna
    Jain, Payal
    Storm, Phillip
    Resnick, Adam
    Waanders, Angela
    NEURO-ONCOLOGY, 2018, 20 : 116 - 116
  • [39] A phase 2 basket trial of an ERK1/2 inhibitor (LY3214996) in combination with abemaciclib for patients whose tumors harbor pathogenic alterations in BRAF, RAF1, MAP2K1/2 ERK1/2, and NF1.
    Taza, Fadi
    Durm, Greg Andrew
    Opyrchal, Mateusz
    Jalal, Shadia Ibrahim
    Radovich, Milan
    Schneider, Bryan P.
    Turk, Anita Ahmed
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [40] Expanding the Spectrum of the Soft Tissue Tumors with Kinase Gene Fusions: A Pediatric Spindle Cell Neoplasm Harboring MTAP-RAF1 Fusion
    Dogukan, Fatih Mert
    Erdem, Zeynep Betuel
    Danyeli, Ayca Ersen
    FETAL AND PEDIATRIC PATHOLOGY, 2023, 42 (03) : 512 - 517