Towards CARS endoscopy

被引：127
|
作者：
Légaré, François
Evans, Conor L.
Ganikhanov, Feruz
Xie, X. Sunney
机构：
[1] Harvard Univ, Ctr Nanoscale Syst, Cambridge, MA 02138 USA
[2] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA
来源：
OPTICS EXPRESS | 2006年 / 14卷 / 10期
关键词：
D O I：
10.1364/OE.14.004427
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We provide a proof-of-principle demonstration of CARS endoscopy. The design utilizes a single mode optical fiber with a focusing unit attached to the distal end. Picosecond pump and Stokes pulse trains in the near infrared are delivered through the fiber with nearly unaltered spectral and temporal characteristics at intensities needed for endoscopy. CARS endoscopic images are recorded by collecting the epi-CARS signal generated at the sample and raster scanning the sample with respect to the fiber. This CARS endoscope prototype represents an important step towards in situ chemically selective imaging for biomedical applications. (c) 2006 Optical Society of America.
引用
收藏
页码：4427 / 4432
页数：6
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