(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methylene]indolin-2-one

被引：4
|
作者：
Zhang, Hongming [1 ]
Ankati, Haribabu [1 ]
Akubathini, Shashidhar Kumar [1 ]
Biehl, Ed [1 ]
机构：
[1] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷
关键词：
KINASE;
D O I：
10.1107/S1600536808040178
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)degrees]. An intramolecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N-H center dot center dot center dot O bonds.
引用
收藏
页码：O8 / U1324
页数：9
相关论文
共 50 条
  • [1] 5-Fluoro-3-(2-phenylhydrazinylidene)indolin-2-one
    Wei, Wen-Bin
    Tian, Shuo
    Shen, Hong
    Sun, Jie
    Wang, Hai-Bo
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1294 - U1765
  • [2] Synthesis and Crystal Structure of (Z)-5-fluoro-3-(phenyl((5-(pyridin-3-ylmethyl)thiophen-2-yl)amino)methylene) Indolin-2-one
    Ding Lei
    Jin Qiu
    Huang Wei
    Tang Feng
    Wei Ping
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2013, 32 (10) : 1586 - 1590
  • [3] Synthesis and Crystal Structure of(Z)-5-fluoro-3-(phenyl((5-(pyridin-3-ylmethyl)thiophen-2-yl)amino)methylene)Indolin-2-one
    丁磊
    金秋
    黄伟
    唐锋
    韦萍
    结构化学, 2013, 32 (10) : 1586 - 1590
  • [4] SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-((1-METHYL-1H-PYRROL-2-YL)METHYLENE)INDOLIN-2-ONE DERIVATIVES AS POTENT ANTICANCER ACTIVE AGENTS
    Wang, Zhen-chao
    Ouyang, Gui-ping
    Chen, Jie
    Hu, Wei-nan
    Xu, Yang
    Li, Wen
    Qi, Ya-yun
    Fu, Yi-hong
    Liu, Jia-min
    HETEROCYCLES, 2019, 98 (08) : 1031 - 1043
  • [5] Five (1H-pyrrol-2-yl)pyridines
    Noland, WE
    Cole, KP
    Britton, D
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2003, 59 : O263 - O267
  • [6] 3,3-bis(1H-indol-3-yl)indolin-2-one
    Selvanayagam, S
    Chandak, MS
    Velmurugan, D
    Ravikumar, K
    Raghunathan, R
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O3122 - O3123
  • [7] Computational study of dynamic motions and possibility of crossing between surfaces in 3-hydroxy-5-(1H-pyrrol-2-yl)-2H-pyrrol-2-one
    Tavakol, Hossein
    MOLECULAR SIMULATION, 2011, 37 (13) : 1113 - 1121
  • [8] (E)-Ethyl 2-cyano-3-(1H-pyrrol-2-yl)-acrylate
    Yuvaraj, Haldorai
    Gayathri, D.
    Kalkhambkar, Rajesh G.
    Gupta, Vivek K.
    Rajnikant
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2135 - U1410
  • [9] CRYSTAL STRUCTURE OF (E)-N′-((1H-PYRROL-2-YL)METHYLENE)-4-HYDROXYBENZOHYDRAZIDE
    Mahmoudi, Ghodrat
    Rostamnia, Sadegh
    Zaragoza, Guillermo
    Brito, Ivan
    Cisterna, Jonathan
    Cardenas, Alejandro
    JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2019, 64 (03): : 4496 - 4501
  • [10] (4-Butoxyphenyl)(1H-pyrrol-2-yl)methanone
    Prakash, V.
    Kapoor, Kamini
    Prakash, M. Shet
    Gupta, Vivek K.
    Kant, Rajni
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1521 - +
12345