Three-component one-pot reaction for the synthesis of β-amide ketones

被引：5
|
作者：
Luo, Yan-Ping [1 ]
Chen, Qiong [2 ]
机构：
[1] Hainan Univ, Key Lab Protect & Dev Utilisat Trop Crop Germplas, Minist Educ, Haikou 570228, Peoples R China
[2] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China
来源：
CHEMICAL PAPERS | 2013年 / 67卷 / 05期
基金：
中国国家自然科学基金;
关键词：
beta-amide ketones; one-pot reaction; synthesis; DAKIN-WEST REACTION; ACETAMIDO KETONES; EFFICIENT; CATALYST; PROPARGYLAMINES; ALDEHYDES; ALKYNES; ACIDS;
D O I：
10.2478/s11696-013-0313-0
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
beta-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by H-1 NMR, C-13 NMR, MS, and elemental analysis.
引用
收藏
页码：532 / 537
页数：6
相关论文
共 50 条
  • [21] One-Pot Three-Component Barbier-Type Reaction for the Synthesis of β-Nitroamines
    Soengas, Raquel G.
    Silva, Artur M. S.
    SYNLETT, 2013, 24 (15) : 1949 - 1952
  • [22] Mechanochemical Thiolation of α-Imino Ketones: A Catalyst-Free, One-Pot, Three-Component Reaction
    Yaragorla, Srinivasarao
    Sulthan, Mahesh
    Vannada, Jagadeshwar
    Arun, Doma
    ACS OMEGA, 2025, 10 (05): : 4636 - 4650
  • [23] Ketones in the catalytic three-component “one-pot” Kabachnik-Fields synthesis of α-amino phosphonates
    E. D. Matveeva
    T. A. Podrugina
    M. V. Prisyajnoy
    N. S. Zefirov
    Russian Chemical Bulletin, 2006, 55 : 1209 - 1214
  • [24] One-pot three-component synthesis of α-methylated ketones from secondary and primary aryl alcohols
    Samser, Shaikh
    Biswal, Priyabrata
    Mohapatra, Omkar
    Pullarat, Sanu Siyad
    Meher, Sushanta Kumar
    Venkatasubbaiah, Krishnan
    NEW JOURNAL OF CHEMISTRY, 2024, 48 (03) : 1320 - 1326
  • [25] Ketones in the catalytic three-component "one-pot" Kabachnik-Fields synthesis of α-amino phosphonates
    Matveeva, E. D.
    Podrugina, T. A.
    Prisyajnoy, M. V.
    Zefirov, N. S.
    RUSSIAN CHEMICAL BULLETIN, 2006, 55 (07) : 1209 - 1214
  • [26] Nanostructured Zirconium Pyrophosphate Catalyzed Diastereoselective Synthesis of β-Amino Ketones via One-Pot Three-Component Mannich Reaction
    Maati, Houda
    Amadine, Othmane
    Essamlali, Younes
    Fihri, Aziz
    Rhihil, Abdallah
    Len, Christophe
    Zahouily, Mohamed
    CATALYSIS LETTERS, 2018, 148 (02) : 699 - 711
  • [27] Nanostructured Zirconium Pyrophosphate Catalyzed Diastereoselective Synthesis of β-Amino Ketones via One-Pot Three-Component Mannich Reaction
    Houda Maati
    Othmane Amadine
    Younes Essamlali
    Aziz Fihri
    Abdallah Rhihil
    Christophe Len
    Mohamed Zahouily
    Catalysis Letters, 2018, 148 : 699 - 711
  • [28] A facile method for the synthesis of nicotinonitriles from ketones via a one-pot chloromethyleneiminium salt mediated three-component reaction
    Asokan, C. V.
    Anabha, E. R.
    Thomas, Ajith Dain
    Jose, Ann Maria
    Lethesh, K. C.
    Prasanth, M.
    Krishanraj, K. U.
    TETRAHEDRON LETTERS, 2007, 48 (32) : 5641 - 5643
  • [29] A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
    Pusch, Stefan
    Opatz, Till
    ORGANIC LETTERS, 2014, 16 (20) : 5430 - 5433
  • [30] One-Pot Three-Component Approach to the Synthesis of Polyfunctional Pyrazoles
    Zhang, Guolin
    Ni, Hangcheng
    Chen, Wenteng
    Shao, Jiaan
    Liu, Huan
    Chen, Binhui
    Yu, Yongping
    ORGANIC LETTERS, 2013, 15 (23) : 5967 - 5969
12345