Gold Nanoparticle Based Plasmon Resonance Light-Scattering Method as a New Approach for Glycogen-Biomacromolecule Interactions

被引：28

作者：

Xiang, Minghui ^{[1
]}

Xu, Xiao ^{[1
]}

Liu, Feng ^{[1
]}

Li, Na ^{[1
]}

Li, Ke-An ^{[1
]}

机构：

[1] Peking Univ, BNLMS, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2009年 / 113卷 / 09期

关键词：

PROTEIN-CARBOHYDRATE INTERACTION; IONIZATION MASS-SPECTROMETRY; CONCANAVALIN-A; GLYCONANOPARTICLES; AFFINITY; SIZE; OLIGOSACCHARIDES; CHROMATOGRAPHY; SPECTROSCOPY;

D O I：

10.1021/jp8065822

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A model was developed for the interactions between glycogen and biomacromolecules by gold nanoparticle plasmon resonance light-scattering method. The interactions between glycogen and biomacromolecules can alter the aggregation status of gold nanoparticles, which produced intensity changes in plasmon resonance light-scattering. This is a sensitive method to study the interactions between glycogen and biomacromolecules from nano- to micromolar level. And it is also a simple method that measurement can be carried out with a common fluorospectrometer using label-free gold nanoparticles as the transducer.

引用

页码：2734 / 2738

页数：5

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