Biocidal Amidic Natural Products

被引：0
|
作者：
Box, Vernon G. S. [1 ]
机构：
[1] CUNY City Coll, Dept Chem, New York, NY 10031 USA
来源：
NATURAL PRODUCT COMMUNICATIONS | 2008年 / 3卷 / 11期
关键词：
Toxic; non-delocalized amides; natural products; molecular modeling; STR3D132.EXE;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Some of the more potent, and interesting, natural products that have marked biocidal properties have one, or more, amide functional groups. On the other hand, there are countless amides that are non-toxic. Thus, there is a need to try to identify the structural features of biocidal amides that could indicate their potential toxicity. A review of the structures of some of these toxic amides, using the molecular modeling program STR3D132, has established that these amide groups are non-de localized.
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页码：1805 / 1812
页数：8
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