Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20, 2015

被引：6

作者：

Wang Qin ^{[2
,3
]}

Zhang Yong ^{[2
,3
]}

Wang Huan Yu ^{[1
,2
,4
]}

Du Hai Jun ^{[1
,2
,4
]}

Nie Kai ^{[1
,2
,3
]}

Song Jing Dong ^{[1
,2
,4
]}

Xiao Kang ^{[1
,2
,4
,5
]}

Lei Wen Wen ^{[1
,2
,4
]}

Guo Jian Qiang ^{[1
,2
,3
]}

Wei He Jiang ^{[1
,2
,3
]}

Cai Kun ^{[1
,2
,3
]}

Wang Yan Hai ^{[1
,2
,3
]}

Wu Jiang ^{[1
,2
,3
]}

Bangura, Gerald ^{[2
]}

Kamara, Idrissa Laybohr ^{[2
]}

Dong Xiao Ping ^{[1
,2
,4
,5
,6
]}

机构：

[1] Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China

[2] Sierra Leone China Friendship Biol Safety Lab, Freetown 999127, Sierra Leone

[3] Natl Hlth & Family Planning Commiss, Key Lab Med Virol, Beijing 102206, Peoples R China

[4] State Key Lab Infect Dis Prevent & Control, Beijing 102206, Peoples R China

[5] Zhejiang Univ, Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou 310003, Zhejiang, Peoples R China

[6] Chinese Acad Sci, Key Lab Pathogen Microbiol & Immunol, Inst Microbiol, Beijing 100101, Peoples R China

来源：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES | 2016年 / 29卷 / 06期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.3967/bes2016.057

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Ebola virus disease reemerged in Western Africa in 2014. Chinese Center for Disease Control and Prevention dispatched the first Ebola virus (EBOV) detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory. The aims of study were to understand epidemiology, clinical manifestations and survival time of EBOV in patient's blood. A total of 913 specimens were tested between March 11 and April 20, 2015. EBOV positivity occurred in 7.37% of the blood and 0.53% in throat swabs. Most commonly reported symptoms of laboratory confirmed patients were intense fatigue, anorexia, and fever. EBOV RNAs persisted in blood for almost 4 weeks and the real-time RT-PCR Ct values showed close correlation with the sampling time after onset.

引用

页码：443 / 447

页数：5

共 14 条

[11] The Transmission Chain Analysis of 2014-2015 Ebola Virus Disease Outbreak in Koinadugu District, Sierra Leone: an Observational Study
Muoghalu, Ifeanyi-Stanley
Moses, Francis
Conteh, Ishata
Swaray, Patrick
Ajudua, Anthonia
Nordstrom, Anders
FRONTIERS IN PUBLIC HEALTH, 2017, 5
[12] The Ebola virus disease outbreak in Tonkolili district, Sierra Leone: a retrospective analysis of the Viral Haemorrhagic Fever surveillance system, July 2014-June 2015
Miglietta, Alessandro
Solimini, Angelo
Dongho, Ghyslaine Bruna Djeunang
Montesano, Carla
Rezza, Giovanni
Vullo, Vincenzo
Colizzi, Vittorio
Russo, Gianluca
EPIDEMIOLOGY AND INFECTION, 2019, 147 : e103
[13] Genome sequence analysis of Ebola virus in clinical samples from three British healthcare workers, August 2014 to March 2015
Bell, A.
Lewandowski, K.
Myers, R.
Wooldridge, D.
Aarons, E.
Simpson, A.
Vipond, R.
Jacobs, M.
Gharbia, S.
Zambon, M.
EUROSURVEILLANCE, 2015, 20 (20) : 6 - 10
[14] Extracting transmission networks from phylogeographic data for epidemic and endemic diseases: Ebola virus in Sierra Leone, 2009 H1N1 pandemic influenza and polio in Nigeria (vol 7, pg 130, 2015)
Famulare, Michael
Hu, Hao
INTERNATIONAL HEALTH, 2015, 7 (04): : 298 - 298

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