Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20, 2015

被引：6

作者：

Wang Qin ^{[2
,3
]}

Zhang Yong ^{[2
,3
]}

Wang Huan Yu ^{[1
,2
,4
]}

Du Hai Jun ^{[1
,2
,4
]}

Nie Kai ^{[1
,2
,3
]}

Song Jing Dong ^{[1
,2
,4
]}

Xiao Kang ^{[1
,2
,4
,5
]}

Lei Wen Wen ^{[1
,2
,4
]}

Guo Jian Qiang ^{[1
,2
,3
]}

Wei He Jiang ^{[1
,2
,3
]}

Cai Kun ^{[1
,2
,3
]}

Wang Yan Hai ^{[1
,2
,3
]}

Wu Jiang ^{[1
,2
,3
]}

Bangura, Gerald ^{[2
]}

Kamara, Idrissa Laybohr ^{[2
]}

Dong Xiao Ping ^{[1
,2
,4
,5
,6
]}

机构：

[1] Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China

[2] Sierra Leone China Friendship Biol Safety Lab, Freetown 999127, Sierra Leone

[3] Natl Hlth & Family Planning Commiss, Key Lab Med Virol, Beijing 102206, Peoples R China

[4] State Key Lab Infect Dis Prevent & Control, Beijing 102206, Peoples R China

[5] Zhejiang Univ, Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou 310003, Zhejiang, Peoples R China

[6] Chinese Acad Sci, Key Lab Pathogen Microbiol & Immunol, Inst Microbiol, Beijing 100101, Peoples R China

来源：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES | 2016年 / 29卷 / 06期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.3967/bes2016.057

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Ebola virus disease reemerged in Western Africa in 2014. Chinese Center for Disease Control and Prevention dispatched the first Ebola virus (EBOV) detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory. The aims of study were to understand epidemiology, clinical manifestations and survival time of EBOV in patient's blood. A total of 913 specimens were tested between March 11 and April 20, 2015. EBOV positivity occurred in 7.37% of the blood and 0.53% in throat swabs. Most commonly reported symptoms of laboratory confirmed patients were intense fatigue, anorexia, and fever. EBOV RNAs persisted in blood for almost 4 weeks and the real-time RT-PCR Ct values showed close correlation with the sampling time after onset.

引用

页码：443 / 447

页数：5

共 14 条

[1] Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20,2015
WANG Qin
ZHANG Yong
WANG Huan Yu
DU Hai Jun
NIE Kai
SONG Jing Dong
XIAO Kang
LEI Wen Wen
GUO Jian Qiang
WEI He Jiang
CAI Kun
WANG Yan Hai
WU Jiang
Gerald BANGURA
Idrissa Laybohr KAMARA
DONG Xiao Ping
BiomedicalandEnvironmentalSciences, 2016, 29 (06) : 443 - 447
[2] Good laboratory practices guarantee biosafety in the Sierra Leone-China friendship biosafety laboratory
Wang, Qin
Zhou, Wei-Min
Zhang, Yong
Wang, Huan-Yu
Du, Hai-Jun
Nie, Kai
Song, Jing-Dong
Xiao, Kang
Lei, Wen-Wen
Guo, Jian-Qiang
Wei, He-Jiang
Cai, Kun
Wang, Yan-Hai
Wu, Jiang
Kamara, Gerard
Kamara, Idrissa
Wei, Qiang
Liang, Mi-Fang
Wu, Gui-Zhen
Dong, Xiao-Ping
INFECTIOUS DISEASES OF POVERTY, 2016, 5
[3] Good laboratory practices guarantee biosafety in the Sierra Leone-China friendship biosafety laboratory
Qin Wang
Wei-Min Zhou
Yong Zhang
Huan-Yu Wang
Hai-Jun Du
Kai Nie
Jing-Dong Song
Kang Xiao
Wen-Wen Lei
Jian-Qiang Guo
He-Jiang Wei
Kun Cai
Yan-Hai Wang
Jiang Wu
Gerard Kamara
Idrissa Kamara
Qiang Wei
Mi-Fang Liang
Gui-Zhen Wu
Xiao-Ping Dong
Infectious Diseases of Poverty, 5
[4] Ebola Virus Diagnostics: The US Centers for Disease Control and Prevention Laboratory in Sierra Leone, August 2014 to March 2015
Flint, Mike
Goodman, Christin H.
Bearden, Scott
Blau, Dianna M.
Amman, Brian R.
Basile, Alison J.
Belser, Jessica A.
Bergeron, Eric
Bowen, Michael D.
Brault, Aaron C.
Campbell, Shelley
Chakrabarti, Ayan K.
Dodd, Kimberly A.
Erickson, Bobbie R.
Freeman, Molly M.
Gibbons, Aridth
Guerrero, Lisa W.
Klena, John D.
Lash, R. Ryan
Lo, Michael K.
McMullan, Laura K.
Momoh, Gbetuwa
Massally, James L.
Goba, Augustine
Paddock, Christopher D.
Priestley, Rachael A.
Pyle, Meredith
Rayfield, Mark
Russell, Brandy J.
Salzer, Johanna S.
Sanchez, Angela J.
Schuh, Amy J.
Sealy, Tara K.
Steinau, Martin
Stoddard, Robyn A.
Taboy, Celine
Turnsek, Maryann
Wang, David
Zemtsova, Galina E.
Zivcec, Marko
Spiropoulou, Christina F.
Stroeher, Ute
Towner, Jonathan S.
Nichol, Stuart T.
Bird, Brian H.
JOURNAL OF INFECTIOUS DISEASES, 2015, 212 : S350 - S358
[5] Rapid deployment of a mobile biosafety level-3 laboratory in Sierra Leone during the 2014 Ebola virus epidemic
Zhang, Yi
Gong, Yan
Wang, Chengyu
Liu, Wensen
Wang, Zhongyi
Xia, Zhiping
Bu, Zhaoyang
Lu, Huijun
Sun, Yang
Zhang, Xiaoguang
Cao, Yuxi
Yang, Fan
Su, Haoxiang
Hu, Yi
Deng, Yongqiang
Zhou, Bo
Zhao, Zongzheng
Fu, Yingying
Kargbo, David
Dafae, Foday
Kargbo, Brima
Kanu, Alex
Liu, Linna
Qian, Jun
Guo, Zhendong
PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (05):
[6] Learning from the challenges of Ebola Virus Disease contact tracers in Sierra Leone, February, 2015
Ilesanmi, Olayinka Stephen
PAN AFRICAN MEDICAL JOURNAL, 2015, 22 : 21
[7] SPATIO-TEMPORAL ANALYSIS OF EBOLA VIRUS DISEASE IN SIERRA LEONE, MAY 2014-SEPTEMBER 2015
Epstein, Adrienne
Castro, Marcia
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 97 (05): : 48 - 49
[8] Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
Furuse, Yuki
Fallah, Mosoka
Oshitani, Hitoshi
Kituyi, Ling
Mahmoud, Nuha
Musa, Emmanuel
Gasasira, Alex
Nyenswah, Tolbert
Dahn, Bernice
Bawo, Luke
PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (07):
[9] Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976
Hofmann-Winkler, Heike
Gnirss, Kerstin
Wrensch, Florian
Poehlmann, Stefan
JOURNAL OF INFECTIOUS DISEASES, 2015, 212 : S172 - S180
[10] Successful Control of Ebola Virus Disease: Analysis of Service Based Data from Rural Sierra Leone
Lokuge, Kamalini
Caleo, Grazia
Greig, Jane
Duncombe, Jennifer
McWilliam, Nicholas
Squire, James
Lamin, Manjo
Veltus, Emily
Wolz, Anja
Kobinger, Gary
de la Vega, Marc-Antoine
Gbabai, Osman
Nabieu, Sao
Lamin, Mohammed
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Danis, Kostas
Banks, Emily
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PLOS NEGLECTED TROPICAL DISEASES, 2016, 10 (03):

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