Functionalization of dihydrodipyridopyrazines involving palladium-catalyzed coupling reactions

被引:11
|
作者
Grig-Alexa, IC
Finaru, AL
Ivan, L
Caubère, P
Guillaumet, G
机构
[1] Univ Orleans, Inst Chim Organ & Analyt, CNRS, UMR 6005, F-45067 Orleans 2, France
[2] Univ Bacau, Lab Sinteza Organ Anal Struct, Bacau 600115, Romania
[3] Univ Bucharest, Fac Chim, Lab Sinteza Organ, Bucharest, Romania
关键词
dihydrodipyridopyrazines; cross-coupling; Stille reaction; Suzuki reaction; Sonogashira reaction; Heck reaction; palladium-catalyzed carbonylation;
D O I
10.1016/j.tetlet.2004.01.092
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Various 4-substituted dihydrodipyridopyrazines were synthesized by palladium-mediated cross-coupling reactions. Starting from the corresponding 4-iodo or 4-bromo derivatives, the incorporation of aryl, vinyl, alkynyl and methoxycarbonyl groups is described. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2343 / 2346
页数:4
相关论文
共 50 条
  • [41] Functionalization at the C3 position of the cephalosporin pharmacophore by palladium-catalyzed cross-coupling reactions
    Faure, Fanny
    Zambon, Margot
    Vo-Hoang, Yen
    Licznar-Fajardo, Patricia
    Docquier, Jean-Denis
    Peyrottes, Suzanne
    Gavara, Laurent
    NEW JOURNAL OF CHEMISTRY, 2025,
  • [42] Recent advancements in palladium-catalyzed reactions involving molecular oxygen
    Ouyang, Lu
    Wu, Wanqing
    CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY, 2017, 7 : 46 - 55
  • [43] Dialyzable carbosilane dendrimers as soluble supports for the functionalization of pyridine fragments via palladium-catalyzed coupling reactions
    Le Nôtre, J
    Firet, JJ
    Sliedregt, LAJM
    van Steen, BJ
    van Koten, G
    Gebbink, RJMK
    ORGANIC LETTERS, 2005, 7 (03) : 363 - 366
  • [44] Palladium-Catalyzed Reactions
    Della Ca, Nicola
    CATALYSTS, 2021, 11 (05)
  • [45] Palladium-Catalyzed Coupling Reactions: Carbonylative Heck Reactions To Give Chalcones
    Wu, Xiao-Feng
    Neumann, Helfried
    Beller, Matthias
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (31) : 5284 - 5288
  • [46] Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions
    Cacchi, Sandro
    Fabrizi, Giancarlo
    CHEMICAL REVIEWS, 2011, 111 : PR215 - PR283
  • [47] Palladium-catalyzed Suzuki-Miyaura coupling reactions involving β,β-dihaloenamides:: Application to the synthesis of disubstituted ynamides
    Couty, S
    Barbazanges, M
    Meyer, C
    Cossy, J
    SYNLETT, 2005, (06) : 905 - 910
  • [48] Palladium-catalyzed carbonylation and coupling reactions of aryl chlorides and amines
    Perry, RJ
    Wilson, BD
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (21): : 7482 - 7485
  • [49] PALLADIUM-CATALYZED CARBON-CARBON COUPLING REACTIONS WITH TETRAARYLBORATES
    CATELLANI, M
    CHIUSOLI, GP
    FORNASARI, V
    GAZZETTA CHIMICA ITALIANA, 1990, 120 (12): : 779 - 781
  • [50] New monoorganostannanes as efficient reagents for palladium-catalyzed coupling reactions
    Fouquet, E
    Pereyre, M
    Rodriguez, AL
    JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (16): : 5242 - 5243