C-H Alkylation of Heteroarenes with Alkyl Oxalates by Molecular Photoelectrocatalysis

被引：27

作者：

Xu, Fan ^{[1
]}

Lai, Xiao-Li ^{[1
]}

Xu, Hai-Chao ^{[1
]}

机构：

[1] Xiamen Univ, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, 422 South Siming Rd, Xiamen 361005, Peoples R China

来源：

SYNLETT | 2021年 / 32卷 / 04期

关键词：

photoelectrochemistry; photoelectrocatalysis; C-H functionalization; alkyl oxalates; heterocycles; PHOTOREDOX CATALYSIS; MINISCI ACYLATION; CARBOXYLIC-ACIDS; LIGHT; ELECTROCHEMISTRY; HETEROCYCLES; ELECTROSYNTHESIS; OXIDATION; RADICALS; ALCOHOLS;

D O I：

10.1055/a-1296-8652

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An oxidant- and metal-free photoelectrocatalytic C-H alkylation reaction of heteroarenes with alkyl oxalates has been developed. Several classes of heteroaromatics, such as quinolines, isoquinolines, pyridines, and phenanthridines, can be alkylated with tertiary or secondary alkyl oxalates. The photoelectrochemical synthesis employs 2,4,5,6-tetra-9H-carbazol-9-ylisophthalonitrile as a molecular catalyst and allows the oxidative transformations to proceed through evolution of hydrogen without a sacrificial chemical oxidant.

引用

页码：369 / 372

页数：4

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