Phase-trafficking reagents and phase-switching strategies for parallel synthesis

被引：0
|
作者：
Flynn, DL [1 ]
机构：
[1] Amgen Inc, Thousand Oaks, CA 91320 USA
来源：
MEDICINAL RESEARCH REVIEWS | 1999年 / 19卷 / 05期
关键词：
D O I：
10.1002/(SICI)1098-1128(199909)19:5<408::AID-MED7>3.0.CO;2-J
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Strategies for the parallel synthesis of small molecule arrays are reviewed with an emphasis on those approaches that integrate the sciences of organic synthesis and product purification. The use of phase-trafficking reagents (PTRs) and phase-switching strategies are highlighted, which allow the rapid, parallel synthesis of small molecule arrays with 'built-in' purification determinants. (C) 1999 John Wiley & Sons, Inc.
引用
收藏
页码：408 / 431
页数：24
相关论文
共 50 条
  • [21] PULMONARY AFFERENT AND CENTRAL INFLUENCES ON RESPIRATORY PHASE-SWITCHING IN THE CAT
    COHEN, MI
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1981, 59 (07) : 675 - 682
  • [22] Involvement of the motor trigeminal nucleus in respiratory phase-switching in the cat
    Pokorski, M
    Gromysz, H
    ACTA NEUROBIOLOGIAE EXPERIMENTALIS, 1997, 57 (01) : 31 - 39
  • [23] Optimal allocation of phase-switching devices for dynamic load balancing
    Victor A. Jimenez
    Adrian L. E. Will
    Electrical Engineering, 2023, 105 : 163 - 173
  • [24] Optimal allocation of phase-switching devices for dynamic load balancing
    Jimenez, Victor A.
    Will, Adrian L. E.
    ELECTRICAL ENGINEERING, 2023, 105 (01) : 163 - 173
  • [25] STUDIES ON RESPIRATORY PHASE-SWITCHING EFFECTS OF NUCLEUS RAPHE MAGNUS
    WANG, YT
    WANG, N
    LIU, L
    KEXUE TONGBAO, 1988, 33 (12): : 1043 - 1048
  • [26] LIMBIC FOREBRAIN AND MIDBRAIN MODULATION AND PHASE-SWITCHING OF EXPIRATORY NEURONS
    DUFFIN, J
    HOCKMAN, CH
    BRAIN RESEARCH, 1972, 39 (01) : 235 - &
  • [27] Reversible fluorous phase-switching of pyridyl-tagged molecules: Applications in organic synthesis and sensing
    Vincent, JM
    El Bakkari, M
    Luguya, R
    Fronton, B
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U3130 - U3130
  • [28] PHASE-SWITCHING OF RESPIRATION INDUCED BY CENTRAL GRAY AND HIPPOCAMPAL STIMULATION IN CAT
    HOCKMAN, CH
    DUFFIN, J
    RUPERT, AH
    VACHON, BR
    JOURNAL OF NEURAL TRANSMISSION, 1974, 35 (04) : 327 - 335
  • [29] Fluorous-tethered quenching reagents for solution phase parallel synthesis
    Lindsley, CW
    Zhao, Z
    Leister, WH
    TETRAHEDRON LETTERS, 2002, 43 (23) : 4225 - 4228
  • [30] Application of Phase-Trafficking Methods to Natural Products Research (vol 73, pg 1568, 2010)
    Araya, Juan J.
    Montenegro, Gloria
    Mitscher, Lester A.
    Timmermann, Barbara N.
    JOURNAL OF NATURAL PRODUCTS, 2011, 74 (04): : 916 - 916
12345