Phase-trafficking reagents and phase-switching strategies for parallel synthesis

被引：0
|
作者：
Flynn, DL [1 ]
机构：
[1] Amgen Inc, Thousand Oaks, CA 91320 USA
来源：
MEDICINAL RESEARCH REVIEWS | 1999年 / 19卷 / 05期
关键词：
D O I：
10.1002/(SICI)1098-1128(199909)19:5<408::AID-MED7>3.0.CO;2-J
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Strategies for the parallel synthesis of small molecule arrays are reviewed with an emphasis on those approaches that integrate the sciences of organic synthesis and product purification. The use of phase-trafficking reagents (PTRs) and phase-switching strategies are highlighted, which allow the rapid, parallel synthesis of small molecule arrays with 'built-in' purification determinants. (C) 1999 John Wiley & Sons, Inc.
引用
收藏
页码：408 / 431
页数：24
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