Natural disasters occur quite often in Indonesia. Relief can he in the forms of logistics or funds. Indonesian Red Cross is one of the institutions most trusted in distributing donations. Unfortunately, there is still no easy facilitation for donors in transferring funds. An effective system is needed to case donors in transferring funds using an online application, to guarantee that the funds are not misused, to inform the kind of disasters requiring financial aids or to report the utilization of the aids. Not many researches have been conducted in this subject. Those related to the Human Computer Interaction in Health Care were focused on patients. The ones in the field of e-commerce were focused on customers. Meanwhile this research on the case of natural disaster was focusing on donors, which was not quite ordinary. The researches in the caseof natural disasters were mostly focusing on the problem of distribution and supply of logistics or searching the nearest locations using GIS. This research aims to explore the user expectations of the mobile apps on the process of donating applying the principles of HCI such as conveniences, effectiveness, security, completeness of information, feedback, and visibility. It also includes the expectations on features for donors and volunteers in using secured payment gateway linked to the bank and on the history of the donation including the channel and their utilization. The result of this research shows that the expected users wish this application could provide quality of information, continuity, easy of acces and high security. The results of Developing a mobile application with effective interaction between the application and the users is included in this paper.