Structure and Dynamics of Ire1 Assembly in the Endoplasmic Reticulum Studied by Molecular Simulation

被引:0
|
作者
Elcock, Adrian H. [1 ]
Kesner, Tamara Frembgen [1 ]
机构
[1] Univ Iowa, Iowa City, IA USA
关键词
D O I
10.1016/j.bpj.2012.11.3208
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:578A / 578A
页数:1
相关论文
共 50 条
  • [41] Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
    Riaz, Thoufiqul Alam
    Junjappa, Raghu Patil
    Handigund, Mallikarjun
    Ferdous, Jannatul
    Kim, Hyung-Ryong
    Chae, Han-Jung
    CELLS, 2020, 9 (05)
  • [42] Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
    Ghosh, Rajarshi
    Wang, Likun
    Wang, Eric S.
    Perera, B. Gayani K.
    Igbaria, Aeid
    Morita, Shuhei
    Prado, Kris
    Thamsen, Maike
    Caswell, Deborah
    Macias, Hector
    Weiberth, Kurt F.
    Gliedt, Micah J.
    Alavi, Marcel V.
    Hari, Sanjay B.
    Mitra, Arinjay K.
    Bhhatarai, Barun
    Schuerer, Stephan C.
    Snapp, Erik L.
    Gould, Douglas B.
    German, Michael S.
    Backes, Bradley J.
    Maly, Dustin J.
    Oakes, Scott A.
    Papa, Feroz R.
    CELL, 2014, 158 (03) : 534 - 548
  • [43] Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA
    Rashid, Harun-Or
    Kim, Hyun-Kyoung
    Junjappa, Raghupatil
    Kim, Hyung-Ryong
    Chae, Han-Jung
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 32 (05) : 981 - 991
  • [44] Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
    Promlek, Thanyarat
    Ishiwata-Kimata, Yuki
    Shido, Masahiro
    Sakuramoto, Mitsuru
    Kohno, Kenji
    Kimata, Yukio
    MOLECULAR BIOLOGY OF THE CELL, 2011, 22 (18) : 3520 - 3532
  • [45] The Endoplasmic Reticulum Stress Sensor IRE1 α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis
    Zhang, Hai-Sheng
    Chen, Ying
    Fan, Li
    Xi, Qiu-Lei
    Wu, Guo-Hao
    Li, Xiu-Xiu
    Yuan, Tang-Long
    He, Sheng-Qi
    Yu, Yue
    Shao, Meng-Le
    Liu, Yang
    Bai, Chen-Guang
    Ling, Zhi-Qiang
    Li, Min
    Liu, Yong
    Fang, Jing
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (24) : 15327 - 15336
  • [46] BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis
    Le Saux, Claude Jourdan
    Ho, Tsung Che
    Brumwell, Alexis M.
    Kathiriya, Jaymin J.
    Wei, Ying
    Hughes, Jun-Wei B.
    Garakani, Kiana
    Atabai, Kamran
    Auyeung, Vincent C.
    Papa, Ferroz R.
    Chapman, Harold A.
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2024, 70 (04) : 247 - 258
  • [47] The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
    Acosta-Alvear, Diego
    Karagoez, G. Elif
    Froehlich, Florian
    Li, Han
    Walther, Tobias C.
    Walter, Peter
    ELIFE, 2018, 7
  • [48] Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
    Adrien Le Thomas
    Elena Ferri
    Scot Marsters
    Jonathan M. Harnoss
    David A. Lawrence
    Iratxe Zuazo-Gaztelu
    Zora Modrusan
    Sara Chan
    Margaret Solon
    Cécile Chalouni
    Weihan Li
    Hartmut Koeppen
    Joachim Rudolph
    Weiru Wang
    Thomas D. Wu
    Peter Walter
    Avi Ashkenazi
    Nature Communications, 12
  • [49] Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
    Sundaram, Arunkumar
    Appathurai, Suhila
    Plumb, Rachel
    Mariappan, Malaiyalam
    MOLECULAR BIOLOGY OF THE CELL, 2018, 29 (11) : 1376 - 1388
  • [50] The Oligomerization Status of IRE1α Kinase/RNase Determines Its Signaling Outputs Under Endoplasmic Reticulum Stress
    Oakes, Scott
    FASEB JOURNAL, 2020, 34