Cerebral Blood Flow and Metabolism in the Developing Fetus

被引：27
|
作者：
du Plessis, Adre J. [1 ,2 ]
机构：
[1] Childrens Hosp Boston, Fetal Neonatal Neurol Res Grp, Dept Neurol, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
来源：
CLINICS IN PERINATOLOGY | 2009年 / 36卷 / 03期
关键词：
Fetal brain; Fetal circulation; Brain development; Fetal hypoxia; Fetal energy metabolism; INTRAUTERINE GROWTH RESTRICTION; GLUCOSE-TRANSPORTER PROTEINS; SKELETAL-MUSCLE ACTIVITY; EARLY MOTOR-ACTIVITY; VELOCITY WAVE-FORMS; FETAL SHEEP; SUSTAINED HYPOXEMIA; OXYGEN-CONSUMPTION; ANGIOTENSIN-II; HEART-RATE;
D O I：
10.1016/j.clp.2009.07.002
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The inaccessibility of the human fetal brain to studies of perfusion and metabolism has impeded progress in the understanding of the normal and abnormal systems of oxygen substrate supply and demand. Consequently, current understanding is based on studies in fetal animals or in the premature infant (ex utero fetus), neither of which is ideal. Despite promising developments in fetal magnetic resonance imaging (MRI) and Doppler ultrasound, major advances in fetal neurodiagnostics will be required before rational and truly informed brainoriented care of the fetus becomes feasible.
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页码：531 / +
页数：19
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